Gene detail

HMPREF0219_RS14465

Histidine kinase, Classic

Clostridioides difficile NAP07 · GCF_000164655

ClassHKTypeClassicLength671 aaTM0ValidatedNoCompleteYesContexttriad
Gene IDGCF_000164655#HMPREF0219_RS14465Stable P2CS identifier used across views.
GenomeGCF_000164655Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0842458Run 6 · 299 sequences · id 100% · cov 80%
External referencesWP_009906364.1 · MIST4 HMPREF0219_RS14465RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length671 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage170 / 671 aa (25.3%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for HMPREF0219_RS14465
Domain-by-domain annotation2 items
1 HisKA#1
449-514 aa · 66 aa · 9.8% of protein
Raw tokenHisKA:449:0.00000000819:514:66:64
2 HATPase_c#2
565-668 aa · 104 aa · 15.5% of protein
Raw tokenHATPase_c:565:4.65e-30:668:104:109
  • Raw architecture: HisKA:449:0.00000000819:514:66:64#HATPase_c:565:4.65e-30:668:104:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labeltriadGCF_000164655::NZ_GG770745.1::G00042
Group size33 locus tags listed below.
HK / RR1 / 2Counts resolved for the local TCS neighborhood.
Context span164810-168304Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF0219_2168RefSeq proteinWP_009906364.1
Context group IDGCF_000164655::NZ_GG770745.1::G00042
Context members
HMPREF0219_RS14470HMPREF0219_RS14465HMPREF0219_RS14460
Partner locus tags
HMPREF0219_RS14470HMPREF0219_RS14465HMPREF0219_RS14460
Partner old locus tags
HMPREF0219_2167HMPREF0219_2168HMPREF0219_2169

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_009906364.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF0219_RS14465Primary locus identifier stored in the genes table.
Old locus tagHMPREF0219_2168Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG770745.1Sequence record reported by the local genomic context database.
Genomic interval165 540-167 555 nt2 016 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span164 810-168 304 ntGCF_000164655::NZ_GG770745.1::G00042

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000164655::NZ_GG770745.1::G00042

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labeltriadNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG770745.1All displayed genes belong to this local TCS context.
Neighborhood span164 810-168 304 nt3 495 nt
Members31 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
164 810 nt168 304 nt
Neighborhood gene cards

3 genes in the current local neighborhood.

HMPREF0219_RS14470GCF_000164655#HMPREF0219_RS14470
RROmpR

164 810-165 490 nt · Reverse (-)

Old locus HMPREF0219_2167RefSeq WP_003417207.1
HMPREF0219_RS14460GCF_000164655#HMPREF0219_RS14460
RROmpR

167 627-168 304 nt · Reverse (-)

Old locus HMPREF0219_2169RefSeq WP_003417201.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0842458Run 6 · HK · 299 sequences
Representative sequenceGCF_000155065#QAE_RS0216030Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0842458

Simplified PFAM architecture for HKOC_0842458

PFAM domain coverage: 170 / 671 aa (25.3%)

1 aa671 aa
HisKA: 450-514 aaHisKAHATPase_c: 563-667 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[450-514] | HATPase_c[563-667]
  • Domain count: 2
  • Matched identifier: HKOC_0842458
  • Positioned domains: HisKA 450-514 ; HATPase_c 563-667
Cluster members and taxonomy
Visualization

Representative gene: GCF_000155065#QAE_RS0216030

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 525 258 · GCF_000164655
AssemblyASM16465v1 · Scaffoldhaploid
Genome composition3 905 466 bp · 28,5% GCClostridioides difficile NAP07
Signal transduction countsGenes 97 · HK 48 · RR 49CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key