Gene detail

HMPREF0219_RS02050

Histidine kinase, Classic

Clostridioides difficile NAP07 · GCF_000164655

ClassHKTypeClassicLength387 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000164655#HMPREF0219_RS02050Stable P2CS identifier used across views.
GenomeGCF_000164655Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2550121Run 6 · 307 sequences · id 100% · cov 80%
External referencesWP_003424698.1 · A0AAX3GVW1 · MIST4 HMPREF0219_RS02050RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKA_3HATPase_c
Protein length387 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage151 / 387 aa (39.0%)Merged over positioned domains only.
Domain description1 HisKA_3,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for HMPREF0219_RS02050
Domain-by-domain annotation2 items
1 HisKA_3#1
188-253 aa · 66 aa · 17.1% of protein
Raw tokenHisKA_3:188:5.14e-21:253:67:68
2 HATPase_c#2
294-378 aa · 85 aa · 22.0% of protein
Raw tokenHATPase_c:294:0.00000000132:378:104:109
  • Raw architecture: HisKA_3:188:5.14e-21:253:67:68#HATPase_c:294:0.00000000132:378:104:109
  • Domain description: 1 HisKA_3,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000164655::NZ_GG770750.1::G00006
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span296646-298449Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF0219_2868RefSeq proteinWP_003424698.1
Context group IDGCF_000164655::NZ_GG770750.1::G00006
Context members
HMPREF0219_RS02050HMPREF0219_RS02045
Partner locus tags
HMPREF0219_RS02050HMPREF0219_RS02045
Partner old locus tags
HMPREF0219_2868HMPREF0219_2869
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003424698.1Primary protein accession used for annex mappings.
UniProt accessionA0AAX3GVW1Primary UniProt accession resolved in the annex database.
UniProt IDA0AAX3GVW1_CLODIDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF0219_RS02050Primary locus identifier stored in the genes table.
Old locus tagHMPREF0219_2868Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG770750.1Sequence record reported by the local genomic context database.
Genomic interval296 646-297 809 nt1 164 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span296 646-298 449 ntGCF_000164655::NZ_GG770750.1::G00006

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000164655::NZ_GG770750.1::G00006

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG770750.1All displayed genes belong to this local TCS context.
Neighborhood span296 646-298 449 nt1 804 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
296 646 nt298 449 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HMPREF0219_RS02045GCF_000164655#HMPREF0219_RS02045
RRNarL

297 802-298 449 nt · Forward (+)

Old locus HMPREF0219_2869RefSeq WP_009905386.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2550121Run 6 · HK · 307 sequences
Representative sequenceGCF_000155065#QAE_RS0206215Use this link to inspect the representative gene detail.
PFAM architectureHisKA_3 + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2550121

Simplified PFAM architecture for HKOC_2550121

PFAM domain coverage: 150 / 387 aa (38.8%)

1 aa387 aa
HisKA_3: 188-252 aaHisKA_3HATPase_c: 294-378 aaHATPase_c
HisKA_3HATPase_c
  • Simplified architecture: HisKA_3 + HATPase_c
  • Raw architecture: HisKA_3[188-252] | HATPase_c[294-378]
  • Domain count: 2
  • Matched identifier: HKOC_2550121
  • Positioned domains: HisKA_3 188-252 ; HATPase_c 294-378
Cluster members and taxonomy
Visualization

Representative gene: GCF_000155065#QAE_RS0206215

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 525 258 · GCF_000164655
AssemblyASM16465v1 · Scaffoldhaploid
Genome composition3 905 466 bp · 28,5% GCClostridioides difficile NAP07
Signal transduction countsGenes 97 · HK 48 · RR 49CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key