Gene detail

HMPREF0219_RS12060

Response regulator OmpR family

Clostridioides difficile NAP07 · GCF_000164655

ClassRRTypeOmpRLength226 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000164655#HMPREF0219_RS12060Stable P2CS identifier used across views.
GenomeGCF_000164655Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterRROC_0924157Run 7 · 306 sequences · id 100% · cov 80%
External referencesWP_009906209.1 · A0AAX3H1L4 · MIST4 HMPREF0219_RS12060RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

Response_regTrans_reg_C
Protein length226 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage184 / 226 aa (81.4%)Merged over positioned domains only.
Domain description1 Response_reg,1 Trans_reg_CSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for HMPREF0219_RS12060
Domain-by-domain annotation2 items
1 Response_reg#1
4-113 aa · 110 aa · 48.7% of protein
Raw tokenResponse_reg:4:4.26e-24:113:111:111
2 Trans_reg_C#2
149-222 aa · 74 aa · 32.7% of protein
Raw tokenTrans_reg_C:149:1.07e-25:222:75:77
  • Raw architecture: Response_reg:4:4.26e-24:113:111:111#Trans_reg_C:149:1.07e-25:222:75:77
  • Domain description: 1 Response_reg,1 Trans_reg_C
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_000164655::NZ_GG770746.1::G00034
Group size11 locus tag listed below.
HK / RR0 / 1Counts resolved for the local TCS neighborhood.
Context span105821-106501Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF0219_0089RefSeq proteinWP_009906209.1
Context group IDGCF_000164655::NZ_GG770746.1::G00034
Context members
HMPREF0219_RS12060
Partner locus tags
HMPREF0219_RS12060
Partner old locus tags
HMPREF0219_0089
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009906209.1Primary protein accession used for annex mappings.
UniProt accessionA0AAX3H1L4Primary UniProt accession resolved in the annex database.
UniProt IDA0AAX3H1L4_CLODIDisplay identifier provided by UniProt.
GO / PubMed5 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF0219_RS12060Primary locus identifier stored in the genes table.
Old locus tagHMPREF0219_0089Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG770746.1Sequence record reported by the local genomic context database.
Genomic interval105 821-106 501 nt681 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span105 821-106 501 ntGCF_000164655::NZ_GG770746.1::G00034

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000164655::NZ_GG770746.1::G00034

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG770746.1All displayed genes belong to this local TCS context.
Neighborhood span105 821-106 501 nt681 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
105 821 nt106 501 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterRROC_0924157Run 7 · RR · 306 sequences
Representative sequenceGCF_033239795#SBI32_RS14975Use this link to inspect the representative gene detail.
PFAM architectureResponse_reg + Trans_reg_C2 domains in the representative PFAM annotation.

PFAM architecture for RROC_0924157

Simplified PFAM architecture for RROC_0924157

PFAM domain coverage: 183 / 239 aa (76.6%)

1 aa239 aa
Response_reg: 4-112 aaResponse_regTrans_reg_C: 150-223 aaTrans_reg_C
Response_regTrans_reg_C
  • Simplified architecture: Response_reg + Trans_reg_C
  • Raw architecture: Response_reg[4-112] | Trans_reg_C[150-223]
  • Domain count: 2
  • Matched identifier: RROC_0924157
  • Positioned domains: Response_reg 4-112 ; Trans_reg_C 150-223
Cluster members and taxonomy
Visualization

Representative gene: GCF_033239795#SBI32_RS14975

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 525 258 · GCF_000164655
AssemblyASM16465v1 · Scaffoldhaploid
Genome composition3 905 466 bp · 28,5% GCClostridioides difficile NAP07
Signal transduction countsGenes 97 · HK 48 · RR 49CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key