Gene detail

HMPREF0219_RS05940

Histidine kinase, Classic

Clostridioides difficile NAP07 · GCF_000164655

ClassHKTypeClassicLength467 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000164655#HMPREF0219_RS05940Stable P2CS identifier used across views.
GenomeGCF_000164655Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1747751Run 6 · 306 sequences · id 100% · cov 80%
External referencesWP_003420354.1 · D5Q6Z1 · MIST4 HMPREF0219_RS05940RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length467 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage241 / 467 aa (51.6%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for HMPREF0219_RS05940
Domain-by-domain annotation3 items
1 HAMP#1
166-232 aa · 67 aa · 14.3% of protein
Raw tokenHAMP:166:0.0000201:232:69:69
2 HisKA#2
245-312 aa · 68 aa · 14.6% of protein
Raw tokenHisKA:245:0.0000000000000228:312:68:64
3 HATPase_c#3
359-464 aa · 106 aa · 22.7% of protein
Raw tokenHATPase_c:359:8.85e-25:464:107:109
  • Raw architecture: HAMP:166:0.0000201:232:69:69#HisKA:245:0.0000000000000228:312:68:64#HATPase_c:359:8.85e-25:464:107:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000164655::NZ_GG770749.1::G00010
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span153724-155856Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF0219_1462RefSeq proteinWP_003420354.1
Context group IDGCF_000164655::NZ_GG770749.1::G00010
Context members
HMPREF0219_RS05945HMPREF0219_RS05940
Partner locus tags
HMPREF0219_RS05945HMPREF0219_RS05940
Partner old locus tags
HMPREF0219_1461HMPREF0219_1462
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003420354.1Primary protein accession used for annex mappings.
UniProt accessionD5Q6Z1Primary UniProt accession resolved in the annex database.
UniProt IDD5Q6Z1_CLODIDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF0219_RS05940Primary locus identifier stored in the genes table.
Old locus tagHMPREF0219_1462Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG770749.1Sequence record reported by the local genomic context database.
Genomic interval154 453-155 856 nt1 404 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span153 724-155 856 ntGCF_000164655::NZ_GG770749.1::G00010

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000164655::NZ_GG770749.1::G00010

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG770749.1All displayed genes belong to this local TCS context.
Neighborhood span153 724-155 856 nt2 133 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
153 724 nt155 856 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HMPREF0219_RS05945GCF_000164655#HMPREF0219_RS05945
RROmpR

153 724-154 449 nt · Forward (+)

Old locus HMPREF0219_1461RefSeq WP_003420352.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1747751Run 6 · HK · 306 sequences
Representative sequenceGCF_000155065#QAE_RS0208280Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1747751

Simplified PFAM architecture for HKOC_1747751

PFAM domain coverage: 172 / 467 aa (36.8%)

1 aa467 aa
HisKA: 245-309 aaHisKAHATPase_c: 359-465 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[245-309] | HATPase_c[359-465]
  • Domain count: 2
  • Matched identifier: HKOC_1747751
  • Positioned domains: HisKA 245-309 ; HATPase_c 359-465
Cluster members and taxonomy
Visualization

Representative gene: GCF_000155065#QAE_RS0208280

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 525 258 · GCF_000164655
AssemblyASM16465v1 · Scaffoldhaploid
Genome composition3 905 466 bp · 28,5% GCClostridioides difficile NAP07
Signal transduction countsGenes 97 · HK 48 · RR 49CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key