Gene detail

HMPREF9551_RS08965

Histidine kinase, Classic

Escherichia coli MS 196-1 · GCF_000164555

ClassHKTypeClassicLength480 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000164555#HMPREF9551_RS08965Stable P2CS identifier used across views.
GenomeGCF_000164555Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Selected clusterHKOC_1618997Run 6 · 2878 sequences · id 100% · cov 80%
External referencesWP_000253839.1 · A0A1X3JKE0 · MIST4 HMPREF9551_RS08965RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length480 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage246 / 480 aa (51.2%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa480 aa
HAMP: 188-257 aa (70 aa)1HisKA: 261-327 aa (67 aa)2HATPase_c: 371-479 aa (109 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
188-257 aa · 70 aa · 14.6% of protein
Raw tokenHAMP:188:0.0000000000623:257:71:69
2 HisKA#2
261-327 aa · 67 aa · 14.0% of protein
Raw tokenHisKA:261:0.0000000000012:327:67:64
3 HATPase_c#3
371-479 aa · 109 aa · 22.7% of protein
Raw tokenHATPase_c:371:3.63e-29:479:110:109
  • Raw architecture: HAMP:188:0.0000000000623:257:71:69#HisKA:261:0.0000000000012:327:67:64#HATPase_c:371:3.63e-29:479:110:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000164555::NZ_GG774065.1::G00018
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span7895-10010Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9551_03525RefSeq proteinWP_000253839.1
Context group IDGCF_000164555::NZ_GG774065.1::G00018
Context members
HMPREF9551_RS08965HMPREF9551_RS08960
Partner locus tags
HMPREF9551_RS08965HMPREF9551_RS08960
Partner old locus tags
HMPREF9551_03525HMPREF9551_03526
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_000253839.1Primary protein accession used for annex mappings.
UniProt accessionA0A1X3JKE0Primary UniProt accession resolved in the annex database.
UniProt IDA0A1X3JKE0_ECOLXDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF9551_RS08965Primary locus identifier stored in the genes table.
Old locus tagHMPREF9551_03525Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG774065.1Sequence record reported by the local genomic context database.
Genomic interval7 895-9 337 nt1 443 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span7 895-10 010 ntGCF_000164555::NZ_GG774065.1::G00018

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000164555::NZ_GG774065.1::G00018

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG774065.1All displayed genes belong to this local TCS context.
Neighborhood span7 895-10 010 nt2 116 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
7 895 nt10 010 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HMPREF9551_RS08960GCF_000164555#HMPREF9551_RS08960
RROmpR

9 327-10 010 nt · Reverse (-)

Old locus HMPREF9551_03526RefSeq WP_000770953.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1618997Run 6 · HK · 2878 sequences
Representative sequenceGCF_000005845#b0570Use this link to inspect the representative gene detail.
PFAM architectureCusS + HAMP + HisKA + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1618997

Simplified PFAM architecture for HKOC_1618997

PFAM domain coverage: 395 / 480 aa (82.3%)

1 aa480 aa
CusS: 8-180 aaCusSHAMP: 210-257 aaHAMPHisKA: 262-326 aaHisKAHATPase_c: 371-479 aaHATPase_c
CusSHAMPHisKAHATPase_c
  • Simplified architecture: CusS + HAMP + HisKA + HATPase_c
  • Raw architecture: CusS[8-180] | HAMP[210-257] | HisKA[262-326] | HATPase_c[371-479]
  • Domain count: 4
  • Matched identifier: HKOC_1618997
  • Positioned domains: CusS 8-180 ; HAMP 210-257 ; HisKA 262-326 ; HATPase_c 371-479
Cluster members and taxonomy
Visualization

Representative gene: GCF_000005845#b0570

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 749 548 · GCF_000164555
AssemblyASM16455v1 · Scaffoldhaploid
Genome composition5 253 182 bp · 50,5% GCEscherichia coli MS 196-1
Signal transduction countsGenes 64 · HK 31 · RR 33CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia

Related genes

Preview from the same derived genome key