1 HisKA#1
244-306 aa · 63 aa · 13.5% of protein
Raw token
HisKA:244:0.000000000000644:306:63:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF9543_RS11675
Histidine kinase, Classic
Escherichia coli MS 146-1 · GCF_000164275
ClassHKTypeClassicLength465 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000164275#HMPREF9543_RS11675Stable P2CS identifier used across views.
GenomeGCF_000164275Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length465 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage170 / 465 aa (36.6%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa465 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
352-458 aa · 107 aa · 23.0% of protein
Raw token
HATPase_c:352:7.94e-34:458:110:109- Raw architecture: HisKA:244:0.000000000000644:306:63:64#HATPase_c:352:7.94e-34:458:110:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000164275::NZ_GG772107.1::G00019
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span3228-5947Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9543_02348RefSeq proteinWP_001211892.1
Context group ID
GCF_000164275::NZ_GG772107.1::G00019Context members
HMPREF9543_RS11680HMPREF9543_RS11675
Partner locus tags
HMPREF9543_RS11680HMPREF9543_RS11675
Partner old locus tags
HMPREF9543_02347HMPREF9543_02348
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_001211892.1Primary protein accession used for annex mappings.
UniProt accessionA0ABD7FFT5Primary UniProt accession resolved in the annex database.
UniProt IDA0ABD7FFT5_ECOLXDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.
Reference hubs
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF9543_RS11675Primary locus identifier stored in the genes table.
Old locus tagHMPREF9543_02348Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG772107.1Sequence record reported by the local genomic context database.
Genomic interval4 550-5 947 nt1 398 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span3 228-5 947 ntGCF_000164275::NZ_GG772107.1::G00019
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000164275::NZ_GG772107.1::G00019Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG772107.1All displayed genes belong to this local TCS context.
Neighborhood span3 228-5 947 nt2 720 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
3 228 nt5 947 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HMPREF9543_RS11680GCF_000164275#HMPREF9543_RS11680
RRNtrC
3 228-4 553 nt · Reverse (-)
HMPREF9543_RS11675GCF_000164275#HMPREF9543_RS11675
HKClassicCurrent focus
4 550-5 947 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1772879
Simplified PFAM architecture for HKOC_1772879
PFAM domain coverage: 168 / 465 aa (36.1%)
1 aa465 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[245-307] | HATPase_c[353-457]
- Domain count: 2
- Matched identifier: HKOC_1772879
- Positioned domains: HisKA 245-307 ; HATPase_c 353-457
Cluster members and taxonomy
Representative gene: GCF_000005845#b4003
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 749 540 · GCF_000164275
AssemblyASM16427v1 · Scaffoldhaploid
Genome composition4 744 342 bp · 50,5% GCEscherichia coli MS 146-1
Signal transduction countsGenes 62 · HK 30 · RR 32CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia
Related genes
Preview from the same derived genome key