1 PAS#1
11-99 aa · 89 aa · 25.5% of protein
Raw token
PAS:11:0.000000682:99:92:113P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF9543_RS00590
Histidine kinase, Classic
Escherichia coli MS 146-1 · GCF_000164275
ClassHKTypeClassicLength349 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000164275#HMPREF9543_RS00590Stable P2CS identifier used across views.
GenomeGCF_000164275Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Domain signature
Compact overview inferred from the domain field
PASHisKAHATPase_c
Protein length349 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage261 / 349 aa (74.8%)Merged over positioned domains only.
Domain description1 PAS,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa349 aa
Domain-by-domain annotation3 items
2 HisKA#2
131-186 aa · 56 aa · 16.0% of protein
Raw token
HisKA:131:0.000000000000602:186:56:643 HATPase_c#3
234-349 aa · 116 aa · 33.2% of protein
Raw token
HATPase_c:234:4.56e-24:349:120:109- Raw architecture: PAS:11:0.000000682:99:92:113#HisKA:131:0.000000000000602:186:56:64#HATPase_c:234:4.56e-24:349:120:109
- Domain description: 1 PAS,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000164275::NZ_GG772161.1::G00001
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span17817-20287Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9543_04929RefSeq proteinWP_000190577.1
Context group ID
GCF_000164275::NZ_GG772161.1::G00001Context members
HMPREF9543_RS00595HMPREF9543_RS00590
Partner locus tags
HMPREF9543_RS00595HMPREF9543_RS00590
Partner old locus tags
HMPREF9543_04928HMPREF9543_04929
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_000190577.1Primary protein accession used for annex mappings.
UniProt accessionA0A8E0KW06Primary UniProt accession resolved in the annex database.
UniProt IDA0A8E0KW06_ECOLXDisplay identifier provided by UniProt.
GO / PubMed5 / 0Unique GO terms and literature references available below.
Reference hubs
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF9543_RS00590Primary locus identifier stored in the genes table.
Old locus tagHMPREF9543_04929Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG772161.1Sequence record reported by the local genomic context database.
Genomic interval19 238-20 287 nt1 050 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span17 817-20 287 ntGCF_000164275::NZ_GG772161.1::G00001
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000164275::NZ_GG772161.1::G00001Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG772161.1All displayed genes belong to this local TCS context.
Neighborhood span17 817-20 287 nt2 471 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
17 817 nt20 287 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HMPREF9543_RS00595GCF_000164275#HMPREF9543_RS00595
RRNtrC
17 817-19 226 nt · Reverse (-)
HMPREF9543_RS00590GCF_000164275#HMPREF9543_RS00590
HKClassicCurrent focus
19 238-20 287 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
PFAM architecturePAS + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2800892
Simplified PFAM architecture for HKOC_2800892
PFAM domain coverage: 260 / 349 aa (74.5%)
1 aa349 aa
PASHisKAHATPase_c
- Simplified architecture: PAS + HisKA + HATPase_c
- Raw architecture: PAS[11-99] | HisKA[131-186] | HATPase_c[234-348]
- Domain count: 3
- Matched identifier: HKOC_2800892
- Positioned domains: PAS 11-99 ; HisKA 131-186 ; HATPase_c 234-348
Cluster members and taxonomy
Representative gene: GCF_000005845#b3869
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 749 540 · GCF_000164275
AssemblyASM16427v1 · Scaffoldhaploid
Genome composition4 744 342 bp · 50,5% GCEscherichia coli MS 146-1
Signal transduction countsGenes 62 · HK 30 · RR 32CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia
Related genes
Preview from the same derived genome key