1 HAMP#1
188-258 aa · 71 aa · 14.4% of protein
Raw token
HAMP:188:0.000000000473:258:71:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF9540_RS21790
Histidine kinase, Classic
Escherichia coli MS 115-1 · GCF_000164235
ClassHKTypeClassicLength493 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000164235#HMPREF9540_RS21790Stable P2CS identifier used across views.
GenomeGCF_000164235Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length493 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage247 / 493 aa (50.1%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa493 aa
Domain-by-domain annotation3 items
2 HisKA#2
262-328 aa · 67 aa · 13.6% of protein
Raw token
HisKA:262:0.00000000000902:328:67:643 HATPase_c#3
372-480 aa · 109 aa · 22.1% of protein
Raw token
HATPase_c:372:4.71e-29:480:110:109- Raw architecture: HAMP:188:0.000000000473:258:71:69#HisKA:262:0.00000000000902:328:67:64#HATPase_c:372:4.71e-29:480:110:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000164235::NZ_GG771730.1::G00037
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span8215-10369Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9540_00116RefSeq proteinWP_000555733.1
Context group ID
GCF_000164235::NZ_GG771730.1::G00037Context members
HMPREF9540_RS21790HMPREF9540_RS21785
Partner locus tags
HMPREF9540_RS21790HMPREF9540_RS21785
Partner old locus tags
HMPREF9540_00116HMPREF9540_00117
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_000555733.1Primary protein accession used for annex mappings.
UniProt accessionA0A602CWR3Primary UniProt accession resolved in the annex database.
UniProt IDA0A602CWR3_SALETDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF9540_RS21790Primary locus identifier stored in the genes table.
Old locus tagHMPREF9540_00116Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG771730.1Sequence record reported by the local genomic context database.
Genomic interval8 215-9 696 nt1 482 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span8 215-10 369 ntGCF_000164235::NZ_GG771730.1::G00037
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000164235::NZ_GG771730.1::G00037Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG771730.1All displayed genes belong to this local TCS context.
Neighborhood span8 215-10 369 nt2 155 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
8 215 nt10 369 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HMPREF9540_RS21790GCF_000164235#HMPREF9540_RS21790
HKClassicCurrent focus
8 215-9 696 nt · Reverse (-)
HMPREF9540_RS21785GCF_000164235#HMPREF9540_RS21785
RROmpR
9 689-10 369 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000164235#HMPREF9540_RS21790The current gene is the representative for this cluster.
PFAM architectureCusS + HAMP + HisKA + HATPase_c4 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1514865
Simplified PFAM architecture for HKOC_1514865
PFAM domain coverage: 399 / 493 aa (80.9%)
1 aa493 aa
CusSHAMPHisKAHATPase_c
- Simplified architecture: CusS + HAMP + HisKA + HATPase_c
- Raw architecture: CusS[8-181] | HAMP[208-257] | HisKA[263-327] | HATPase_c[372-481]
- Domain count: 4
- Matched identifier: HKOC_1514865
- Positioned domains: CusS 8-181 ; HAMP 208-257 ; HisKA 263-327 ; HATPase_c 372-481
Cluster members and taxonomy
Representative gene: GCF_000164235#HMPREF9540_RS21790
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 749 537 · GCF_000164235
AssemblyASM16423v1 · Scaffoldhaploid
Genome composition4 822 312 bp · 51,0% GCEscherichia coli MS 115-1
Signal transduction countsGenes 62 · HK 30 · RR 32CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia
Related genes
Preview from the same derived genome key