1 HAMP#1
179-244 aa · 66 aa · 13.7% of protein
Raw token
HAMP:179:0.000000000000429:244:66:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
EFRG_RS08740
Histidine kinase, Classic
Enterococcus faecium 1,231,501 · GCF_000157555
ClassHKTypeClassicLength482 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000157555#EFRG_RS08740Stable P2CS identifier used across views.
GenomeGCF_000157555Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length482 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage243 / 482 aa (50.4%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa482 aa
Domain-by-domain annotation3 items
2 HisKA#2
255-321 aa · 67 aa · 13.9% of protein
Raw token
HisKA:255:0.00000000000000157:321:67:643 HATPase_c#3
366-475 aa · 110 aa · 22.8% of protein
Raw token
HATPase_c:366:5.74e-32:475:110:109- Raw architecture: HAMP:179:0.000000000000429:244:66:69#HisKA:255:0.00000000000000157:321:67:64#HATPase_c:366:5.74e-32:475:110:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000157555::NZ_GG688436.1::G00018
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span585090-587254Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEFRG_00582RefSeq proteinWP_002302594.1
Context group ID
GCF_000157555::NZ_GG688436.1::G00018Context members
EFRG_RS08735EFRG_RS08740
Partner locus tags
EFRG_RS08735EFRG_RS08740
Partner old locus tags
EFRG_00581EFRG_00582
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_002302594.1Primary protein accession used for annex mappings.
UniProt accessionA0A2C9X433Primary UniProt accession resolved in the annex database.
UniProt IDA0A2C9X433_ENTFCDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
Reference hubs
GO terms
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagEFRG_RS08740Primary locus identifier stored in the genes table.
Old locus tagEFRG_00582Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG688436.1Sequence record reported by the local genomic context database.
Genomic interval585 806-587 254 nt1 449 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span585 090-587 254 ntGCF_000157555::NZ_GG688436.1::G00018
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000157555::NZ_GG688436.1::G00018Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG688436.1All displayed genes belong to this local TCS context.
Neighborhood span585 090-587 254 nt2 165 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
585 090 nt587 254 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
EFRG_RS08735GCF_000157555#EFRG_RS08735
RROmpR
585 090-585 806 nt · Forward (+)
EFRG_RS08740GCF_000157555#EFRG_RS08740
HKClassicCurrent focus
585 806-587 254 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000157555#EFRG_RS08740The current gene is the representative for this cluster.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1602512
Simplified PFAM architecture for HKOC_1602512
PFAM domain coverage: 225 / 482 aa (46.7%)
1 aa482 aa
HAMPHisKAHATPase_c
- Simplified architecture: HAMP + HisKA + HATPase_c
- Raw architecture: HAMP[194-243] | HisKA[256-320] | HATPase_c[367-476]
- Domain count: 3
- Matched identifier: HKOC_1602512
- Positioned domains: HAMP 194-243 ; HisKA 256-320 ; HATPase_c 367-476
Cluster members and taxonomy
Representative gene: GCF_000157555#EFRG_RS08740
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 565 658 · GCF_000157555
AssemblyASM15755v1 · Scaffoldhaploid
Genome composition2 871 230 bp · 38,0% GCEnterococcus faecium 1,231,501
Signal transduction countsGenes 41 · HK 19 · RR 22CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus
Related genes
Preview from the same derived genome key