1 sCache_like#1
35-151 aa · 117 aa · 20.2% of protein
Raw token
sCache_like:35:5.09e-36:151:117:114P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
EFRG_RS08100
Histidine kinase, Classic
Enterococcus faecium 1,231,501 · GCF_000157555
ClassHKTypeClassicLength578 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000157555#EFRG_RS08100Stable P2CS identifier used across views.
GenomeGCF_000157555Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Domain signature
Compact overview inferred from the domain field
sCache_likeHisKAHATPase_c
Protein length578 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage286 / 578 aa (49.5%)Merged over positioned domains only.
Domain description1 sCache_like,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa578 aa
Domain-by-domain annotation3 items
2 HisKA#2
360-422 aa · 63 aa · 10.9% of protein
Raw token
HisKA:360:0.0000000000000509:422:63:643 HATPase_c#3
471-576 aa · 106 aa · 18.3% of protein
Raw token
HATPase_c:471:1.54e-30:576:107:109- Raw architecture: sCache_like:35:5.09e-36:151:117:114#HisKA:360:0.0000000000000509:422:63:64#HATPase_c:471:1.54e-30:576:107:109
- Domain description: 1 sCache_like,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000157555::NZ_GG688436.1::G00016
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span464712-467149Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEFRG_00447RefSeq proteinWP_002306266.1
Context group ID
GCF_000157555::NZ_GG688436.1::G00016Context members
EFRG_RS08100EFRG_RS08105
Partner locus tags
EFRG_RS08100EFRG_RS08105
Partner old locus tags
EFRG_00447EFRG_00448
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_002306266.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagEFRG_RS08100Primary locus identifier stored in the genes table.
Old locus tagEFRG_00447Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG688436.1Sequence record reported by the local genomic context database.
Genomic interval464 712-466 448 nt1 737 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span464 712-467 149 ntGCF_000157555::NZ_GG688436.1::G00016
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000157555::NZ_GG688436.1::G00016Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG688436.1All displayed genes belong to this local TCS context.
Neighborhood span464 712-467 149 nt2 438 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
464 712 nt467 149 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
EFRG_RS08100GCF_000157555#EFRG_RS08100
HKClassicCurrent focus
464 712-466 448 nt · Reverse (-)
EFRG_RS08105GCF_000157555#EFRG_RS08105
RROmpR
466 445-467 149 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000157555#EFRG_RS08100The current gene is the representative for this cluster.
PFAM architecturesCache_like + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1172276
Simplified PFAM architecture for HKOC_1172276
PFAM domain coverage: 277 / 578 aa (47.9%)
1 aa578 aa
sCache_likeHisKAHATPase_c
- Simplified architecture: sCache_like + HisKA + HATPase_c
- Raw architecture: sCache_like[38-143] | HisKA[360-423] | HATPase_c[471-577]
- Domain count: 3
- Matched identifier: HKOC_1172276
- Positioned domains: sCache_like 38-143 ; HisKA 360-423 ; HATPase_c 471-577
Cluster members and taxonomy
Representative gene: GCF_000157555#EFRG_RS08100
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 565 658 · GCF_000157555
AssemblyASM15755v1 · Scaffoldhaploid
Genome composition2 871 230 bp · 38,0% GCEnterococcus faecium 1,231,501
Signal transduction countsGenes 41 · HK 19 · RR 22CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus
Related genes
Preview from the same derived genome key