1 HAMP#1
288-360 aa · 73 aa · 12.7% of protein
Raw token
HAMP:288:0.0000000936:360:73:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
EFKG_RS12460
Histidine kinase, Classic
Enterococcus faecalis Fly1 · GCF_000157415
ClassHKTypeClassicLength576 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000157415#EFKG_RS12460Stable P2CS identifier used across views.
GenomeGCF_000157415Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Domain signature
Compact overview inferred from the domain field
HAMPHis_kinaseHATPase_c
Protein length576 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage263 / 576 aa (45.7%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa576 aa
Domain-by-domain annotation3 items
2 His_kinase#2
375-453 aa · 79 aa · 13.7% of protein
Raw token
His_kinase:375:8.52e-28:453:80:803 HATPase_c#3
464-574 aa · 111 aa · 19.3% of protein
Raw token
HATPase_c:464:0.0000000000296:574:113:109- Raw architecture: HAMP:288:0.0000000936:360:73:69#His_kinase:375:8.52e-28:453:80:80#HATPase_c:464:0.0000000000296:574:113:109
- Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000157415::NZ_GG692670.1::G00002
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span539942-543165Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEFKG_00498RefSeq proteinWP_016616168.1
Context group ID
GCF_000157415::NZ_GG692670.1::G00002Context members
EFKG_RS12460EFKG_RS12465
Partner locus tags
EFKG_RS12460EFKG_RS12465
Partner old locus tags
EFKG_00498EFKG_00499
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_016616168.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagEFKG_RS12460Primary locus identifier stored in the genes table.
Old locus tagEFKG_00498Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG692670.1Sequence record reported by the local genomic context database.
Genomic interval539 942-541 672 nt1 731 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span539 942-543 165 ntGCF_000157415::NZ_GG692670.1::G00002
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000157415::NZ_GG692670.1::G00002Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG692670.1All displayed genes belong to this local TCS context.
Neighborhood span539 942-543 165 nt3 224 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
539 942 nt543 165 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
EFKG_RS12460GCF_000157415#EFKG_RS12460
HKClassicCurrent focus
539 942-541 672 nt · Forward (+)
EFKG_RS12465GCF_000157415#EFKG_RS12465
RRunclassified
541 684-543 165 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000157415#EFKG_RS12460The current gene is the representative for this cluster.
PFAM architectureHis_kinase + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1182910
Simplified PFAM architecture for HKOC_1182910
PFAM domain coverage: 180 / 576 aa (31.3%)
1 aa576 aa
His_kinaseHATPase_c
- Simplified architecture: His_kinase + HATPase_c
- Raw architecture: His_kinase[375-453] | HATPase_c[474-574]
- Domain count: 2
- Matched identifier: HKOC_1182910
- Positioned domains: His_kinase 375-453 ; HATPase_c 474-574
Cluster members and taxonomy
Representative gene: GCF_000157415#EFKG_RS12460
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 565 649 · GCF_000157415
AssemblyASM15741v1 · Scaffoldhaploid
Genome composition2 834 288 bp · 37,5% GCEnterococcus faecalis Fly1
Signal transduction countsGenes 35 · HK 16 · RR 19CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus
Related genes
Preview from the same derived genome key