Gene detail

EFKG_RS06245

Histidine kinase, Classic

Enterococcus faecalis Fly1 · GCF_000157415

ClassHKTypeClassicLength447 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000157415#EFKG_RS06245Stable P2CS identifier used across views.
GenomeGCF_000157415Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Selected clusterHKOC_1999541Run 6 · 18 sequences · id 100% · cov 80% · representative
External referencesWP_025187157.1 · MIST4 EFKG_RS06245RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length447 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage258 / 447 aa (57.7%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa447 aa
HAMP: 130-208 aa (79 aa)1HisKA: 220-284 aa (65 aa)2HATPase_c: 329-442 aa (114 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
130-208 aa · 79 aa · 17.7% of protein
Raw tokenHAMP:130:0.00000019:208:79:69
2 HisKA#2
220-284 aa · 65 aa · 14.5% of protein
Raw tokenHisKA:220:0.0000000000000113:284:65:64
3 HATPase_c#3
329-442 aa · 114 aa · 25.5% of protein
Raw tokenHATPase_c:329:1.85e-32:442:114:109
  • Raw architecture: HAMP:130:0.00000019:208:79:69#HisKA:220:0.0000000000000113:284:65:64#HATPase_c:329:1.85e-32:442:114:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000157415::NZ_GG692665.1::G00013
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span53628-55660Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEFKG_01528RefSeq proteinWP_025187157.1
Context group IDGCF_000157415::NZ_GG692665.1::G00013
Context members
EFKG_RS06240EFKG_RS06245
Partner locus tags
EFKG_RS06240EFKG_RS06245
Partner old locus tags
EFKG_01527EFKG_01528
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_025187157.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagEFKG_RS06245Primary locus identifier stored in the genes table.
Old locus tagEFKG_01528Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG692665.1Sequence record reported by the local genomic context database.
Genomic interval54 317-55 660 nt1 344 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span53 628-55 660 ntGCF_000157415::NZ_GG692665.1::G00013

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000157415::NZ_GG692665.1::G00013

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG692665.1All displayed genes belong to this local TCS context.
Neighborhood span53 628-55 660 nt2 033 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
53 628 nt55 660 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

EFKG_RS06240GCF_000157415#EFKG_RS06240
RROmpR

53 628-54 320 nt · Reverse (-)

Old locus EFKG_01527RefSeq WP_002355236.1
EFKG_RS06245GCF_000157415#EFKG_RS06245
HKClassicCurrent focus

54 317-55 660 nt · Reverse (-)

Old locus EFKG_01528RefSeq WP_025187157.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1999541Run 6 · HK · 18 sequences
Representative sequenceGCF_000157415#EFKG_RS06245The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1999541

Simplified PFAM architecture for HKOC_1999541

PFAM domain coverage: 178 / 447 aa (39.8%)

1 aa447 aa
HisKA: 220-284 aaHisKAHATPase_c: 330-442 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[220-284] | HATPase_c[330-442]
  • Domain count: 2
  • Matched identifier: HKOC_1999541
  • Positioned domains: HisKA 220-284 ; HATPase_c 330-442
Cluster members and taxonomy
Visualization

Representative gene: GCF_000157415#EFKG_RS06245

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 565 649 · GCF_000157415
AssemblyASM15741v1 · Scaffoldhaploid
Genome composition2 834 288 bp · 37,5% GCEnterococcus faecalis Fly1
Signal transduction countsGenes 35 · HK 16 · RR 19CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus

Related genes

Preview from the same derived genome key