Gene detail

EFHG_RS11250

Histidine kinase, Classic

Enterococcus faecalis HIP11704 · GCF_000157335

ClassHKTypeClassicLength576 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000157335#EFHG_RS11250Stable P2CS identifier used across views.
GenomeGCF_000157335Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Selected clusterHKOC_1182892Run 6 · 103 sequences · id 100% · cov 80%
External referencesWP_002403068.1 · MIST4 EFHG_RS11250RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHis_kinaseHATPase_c
Protein length576 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage263 / 576 aa (45.7%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa576 aa
HAMP: 288-360 aa (73 aa)1His_kinase: 375-453 aa (79 aa)2HATPase_c: 464-574 aa (111 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
288-360 aa · 73 aa · 12.7% of protein
Raw tokenHAMP:288:0.0000000815:360:73:69
2 His_kinase#2
375-453 aa · 79 aa · 13.7% of protein
Raw tokenHis_kinase:375:8.06e-28:453:80:80
3 HATPase_c#3
464-574 aa · 111 aa · 19.3% of protein
Raw tokenHATPase_c:464:0.00000000000865:574:113:109
  • Raw architecture: HAMP:288:0.0000000815:360:73:69#His_kinase:375:8.06e-28:453:80:80#HATPase_c:464:0.00000000000865:574:113:109
  • Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_000157335::NZ_GG692646.1::G00011
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span117154-118884Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEFHG_00961RefSeq proteinWP_002403068.1
Context group IDGCF_000157335::NZ_GG692646.1::G00011
Context members
EFHG_RS11250
Partner locus tags
EFHG_RS11250
Partner old locus tags
EFHG_00961
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_002403068.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagEFHG_RS11250Primary locus identifier stored in the genes table.
Old locus tagEFHG_00961Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG692646.1Sequence record reported by the local genomic context database.
Genomic interval117 154-118 884 nt1 731 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span117 154-118 884 ntGCF_000157335::NZ_GG692646.1::G00011

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000157335::NZ_GG692646.1::G00011

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG692646.1All displayed genes belong to this local TCS context.
Neighborhood span117 154-118 884 nt1 731 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
117 154 nt118 884 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

EFHG_RS11250GCF_000157335#EFHG_RS11250
HKClassicCurrent focus

117 154-118 884 nt · Reverse (-)

Old locus EFHG_00961RefSeq WP_002403068.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1182892Run 6 · HK · 103 sequences
Representative sequenceGCF_000148045#HMPREF9514_RS09190Use this link to inspect the representative gene detail.
PFAM architectureHis_kinase + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1182892

Simplified PFAM architecture for HKOC_1182892

PFAM domain coverage: 180 / 576 aa (31.3%)

1 aa576 aa
His_kinase: 375-453 aaHis_kinaseHATPase_c: 474-574 aaHATPase_c
His_kinaseHATPase_c
  • Simplified architecture: His_kinase + HATPase_c
  • Raw architecture: His_kinase[375-453] | HATPase_c[474-574]
  • Domain count: 2
  • Matched identifier: HKOC_1182892
  • Positioned domains: His_kinase 375-453 ; HATPase_c 474-574
Cluster members and taxonomy
Visualization

Representative gene: GCF_000148045#HMPREF9514_RS09190

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 565 646 · GCF_000157335
AssemblyASM15733v1 · Scaffoldhaploid
Genome composition3 202 994 bp · 37,0% GCEnterococcus faecalis HIP11704
Signal transduction countsGenes 30 · HK 14 · RR 16CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus

Related genes

Preview from the same derived genome key