Gene detail

ROSINTL182_RS22065

Histidine kinase, Classic

Roseburia intestinalis L1-82 · GCF_000156535

ClassHKTypeClassicLength287 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000156535#ROSINTL182_RS22065Stable P2CS identifier used across views.
GenomeGCF_000156535Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Roseburia
Selected clusterHKOC_1013078Run 6 · 11 sequences · id 100% · cov 80%
External referencesWP_044999489.1 · MIST4 ROSINTL182_RS22065RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHis_kinaseHATPase_c
Protein length287 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage248 / 287 aa (86.4%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa287 aa
HAMP: 2-56 aa (55 aa)1His_kinase: 71-150 aa (80 aa)2HATPase_c: 166-278 aa (113 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
2-56 aa · 55 aa · 19.2% of protein
Raw tokenHAMP:2:0.000000000615:56:55:69
2 His_kinase#2
71-150 aa · 80 aa · 27.9% of protein
Raw tokenHis_kinase:71:1.14e-26:150:80:80
3 HATPase_c#3
166-278 aa · 113 aa · 39.4% of protein
Raw tokenHATPase_c:166:0.00000000000161:278:116:109
  • Raw architecture: HAMP:2:0.000000000615:56:55:69#His_kinase:71:1.14e-26:150:80:80#HATPase_c:166:0.00000000000161:278:116:109
  • Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_000156535::NZ_GG692743.1::G00019
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span29652-30517Genomic interval covered by the local TCS group.
Identifiers
Old locus tagROSINTL182_08731RefSeq proteinWP_044999489.1
Context group IDGCF_000156535::NZ_GG692743.1::G00019
Context members
ROSINTL182_RS22065
Partner locus tags
ROSINTL182_RS22065
Partner old locus tags
ROSINTL182_08731
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_044999489.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagROSINTL182_RS22065Primary locus identifier stored in the genes table.
Old locus tagROSINTL182_08731Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG692743.1Sequence record reported by the local genomic context database.
Genomic interval29 652-30 517 nt866 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span29 652-30 517 ntGCF_000156535::NZ_GG692743.1::G00019

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000156535::NZ_GG692743.1::G00019

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG692743.1All displayed genes belong to this local TCS context.
Neighborhood span29 652-30 517 nt866 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
29 652 nt30 517 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1013078Run 6 · HK · 11 sequences
Representative sequenceGCF_000209995#ROI_RS09340Use this link to inspect the representative gene detail.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1013078

Simplified PFAM architecture for HKOC_1013078

PFAM domain coverage: 243 / 608 aa (40.0%)

1 aa608 aa
HAMP: 324-377 aaHAMPHis_kinase: 392-470 aaHis_kinaseHATPase_c: 487-596 aaHATPase_c
HAMPHis_kinaseHATPase_c
  • Simplified architecture: HAMP + His_kinase + HATPase_c
  • Raw architecture: HAMP[324-377] | His_kinase[392-470] | HATPase_c[487-596]
  • Domain count: 3
  • Matched identifier: HKOC_1013078
  • Positioned domains: HAMP 324-377 ; His_kinase 392-470 ; HATPase_c 487-596
Cluster members and taxonomy
Visualization

Representative gene: GCF_000209995#ROI_RS09340

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 536 231 · GCF_000156535
AssemblyASM15653v1 · Scaffoldhaploid
Genome composition4 411 375 bp · 42,5% GCRoseburia intestinalis L1-82
Signal transduction countsGenes 112 · HK 51 · RR 58CheA 1 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusRoseburia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Roseburia

Related genes

Preview from the same derived genome key