1 dCache_1#1
55-293 aa · 239 aa · 39.0% of protein
Raw token
dCache_1:55:1.9e-17:293:243:195P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
ROSINTL182_RS02245
Histidine kinase, Classic
Roseburia intestinalis L1-82 · GCF_000156535
ClassHKTypeClassicLength613 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000156535#ROSINTL182_RS02245Stable P2CS identifier used across views.
GenomeGCF_000156535Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Roseburia
Domain signature
Compact overview inferred from the domain field
dCache_1His_kinaseHATPase_c
Protein length613 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage425 / 613 aa (69.3%)Merged over positioned domains only.
Domain description1 dCache_1,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa613 aa
Domain-by-domain annotation3 items
2 His_kinase#2
394-473 aa · 80 aa · 13.1% of protein
Raw token
His_kinase:394:3.32e-34:473:80:803 HATPase_c#3
489-594 aa · 106 aa · 17.3% of protein
Raw token
HATPase_c:489:9.02e-19:594:109:109- Raw architecture: dCache_1:55:1.9e-17:293:243:195#His_kinase:394:3.32e-34:473:80:80#HATPase_c:489:9.02e-19:594:109:109
- Domain description: 1 dCache_1,1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000156535::NZ_GG692714.1::G00064
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span195946-199385Genomic interval covered by the local TCS group.
Identifiers
Old locus tagROSINTL182_05503RefSeq proteinWP_006855630.1
Context group ID
GCF_000156535::NZ_GG692714.1::G00064Context members
ROSINTL182_RS02245ROSINTL182_RS02250
Partner locus tags
ROSINTL182_RS02245ROSINTL182_RS02250
Partner old locus tags
ROSINTL182_05503ROSINTL182_05504
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_006855630.1Primary protein accession used for annex mappings.
UniProt accessionC7G6I9Primary UniProt accession resolved in the annex database.
UniProt IDC7G6I9_9FIRMDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagROSINTL182_RS02245Primary locus identifier stored in the genes table.
Old locus tagROSINTL182_05503Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG692714.1Sequence record reported by the local genomic context database.
Genomic interval195 946-197 787 nt1 842 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span195 946-199 385 ntGCF_000156535::NZ_GG692714.1::G00064
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000156535::NZ_GG692714.1::G00064Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG692714.1All displayed genes belong to this local TCS context.
Neighborhood span195 946-199 385 nt3 440 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
195 946 nt199 385 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
ROSINTL182_RS02245GCF_000156535#ROSINTL182_RS02245
HKClassicCurrent focus
195 946-197 787 nt · Reverse (-)
ROSINTL182_RS02250GCF_000156535#ROSINTL182_RS02250
RRunclassified
197 784-199 385 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000156535#ROSINTL182_RS02245The current gene is the representative for this cluster.
PFAM architecturedCache_1 + His_kinase + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0993932
Simplified PFAM architecture for HKOC_0993932
PFAM domain coverage: 414 / 613 aa (67.5%)
1 aa613 aa
dCache_1His_kinaseHATPase_c
- Simplified architecture: dCache_1 + His_kinase + HATPase_c
- Raw architecture: dCache_1[63-293] | His_kinase[394-471] | HATPase_c[490-594]
- Domain count: 3
- Matched identifier: HKOC_0993932
- Positioned domains: dCache_1 63-293 ; His_kinase 394-471 ; HATPase_c 490-594
Cluster members and taxonomy
Representative gene: GCF_000156535#ROSINTL182_RS02245
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 536 231 · GCF_000156535
AssemblyASM15653v1 · Scaffoldhaploid
Genome composition4 411 375 bp · 42,5% GCRoseburia intestinalis L1-82
Signal transduction countsGenes 112 · HK 51 · RR 58CheA 1 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusRoseburia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Roseburia
Related genes
Preview from the same derived genome key