1 HAMP#1
187-258 aa · 72 aa · 14.8% of protein
Raw token
HAMP:187:0.00000000233:258:72:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
ROSINTL182_RS17725
Histidine kinase, Classic
Roseburia intestinalis L1-82 · GCF_000156535
ClassHKTypeClassicLength485 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000156535#ROSINTL182_RS17725Stable P2CS identifier used across views.
GenomeGCF_000156535Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Roseburia
Domain signature
Compact overview inferred from the domain field
HAMPHis_kinaseHATPase_c
Protein length485 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage260 / 485 aa (53.6%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa485 aa
Domain-by-domain annotation3 items
2 His_kinase#2
275-354 aa · 80 aa · 16.5% of protein
Raw token
His_kinase:275:1.74e-34:354:80:803 HATPase_c#3
374-481 aa · 108 aa · 22.3% of protein
Raw token
HATPase_c:374:2.31e-16:481:108:109- Raw architecture: HAMP:187:0.00000000233:258:72:69#His_kinase:275:1.74e-34:354:80:80#HATPase_c:374:2.31e-16:481:108:109
- Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000156535::NZ_GG692750.1::G00012
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1874-4962Genomic interval covered by the local TCS group.
Identifiers
Old locus tagROSINTL182_08978RefSeq proteinWP_006859060.1
Context group ID
GCF_000156535::NZ_GG692750.1::G00012Context members
ROSINTL182_RS17725ROSINTL182_RS17730
Partner locus tags
ROSINTL182_RS17725ROSINTL182_RS17730
Partner old locus tags
ROSINTL182_08978ROSINTL182_08979
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_006859060.1Primary protein accession used for annex mappings.
UniProt accessionC7GGB0Primary UniProt accession resolved in the annex database.
UniProt IDC7GGB0_9FIRMDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagROSINTL182_RS17725Primary locus identifier stored in the genes table.
Old locus tagROSINTL182_08978Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG692750.1Sequence record reported by the local genomic context database.
Genomic interval1 874-3 331 nt1 458 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span1 874-4 962 ntGCF_000156535::NZ_GG692750.1::G00012
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000156535::NZ_GG692750.1::G00012Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG692750.1All displayed genes belong to this local TCS context.
Neighborhood span1 874-4 962 nt3 089 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 874 nt4 962 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
ROSINTL182_RS17725GCF_000156535#ROSINTL182_RS17725
HKClassicCurrent focus
1 874-3 331 nt · Reverse (-)
ROSINTL182_RS17730GCF_000156535#ROSINTL182_RS17730
RRunclassified
3 328-4 962 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000156535#ROSINTL182_RS17725The current gene is the representative for this cluster.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1575875
Simplified PFAM architecture for HKOC_1575875
PFAM domain coverage: 232 / 485 aa (47.8%)
1 aa485 aa
HAMPHis_kinaseHATPase_c
- Simplified architecture: HAMP + His_kinase + HATPase_c
- Raw architecture: HAMP[213-258] | His_kinase[275-352] | HATPase_c[373-480]
- Domain count: 3
- Matched identifier: HKOC_1575875
- Positioned domains: HAMP 213-258 ; His_kinase 275-352 ; HATPase_c 373-480
Cluster members and taxonomy
Representative gene: GCF_000156535#ROSINTL182_RS17725
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 536 231 · GCF_000156535
AssemblyASM15653v1 · Scaffoldhaploid
Genome composition4 411 375 bp · 42,5% GCRoseburia intestinalis L1-82
Signal transduction countsGenes 112 · HK 51 · RR 58CheA 1 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusRoseburia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Roseburia
Related genes
Preview from the same derived genome key