1 HAMP#1
179-244 aa · 66 aa · 13.8% of protein
Raw token
HAMP:179:0.00000000000216:244:70:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
ROSINTL182_RS17460
Histidine kinase, Classic
Roseburia intestinalis L1-82 · GCF_000156535
ClassHKTypeClassicLength478 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000156535#ROSINTL182_RS17460Stable P2CS identifier used across views.
GenomeGCF_000156535Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Roseburia
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length478 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage244 / 478 aa (51.0%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa478 aa
Domain-by-domain annotation3 items
2 HisKA#2
249-313 aa · 65 aa · 13.6% of protein
Raw token
HisKA:249:1.72e-16:313:65:643 HATPase_c#3
360-472 aa · 113 aa · 23.6% of protein
Raw token
HATPase_c:360:4.16e-32:472:113:109- Raw architecture: HAMP:179:0.00000000000216:244:70:69#HisKA:249:1.72e-16:313:65:64#HATPase_c:360:4.16e-32:472:113:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000156535::NZ_GG692748.1::G00015
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span16656-18793Genomic interval covered by the local TCS group.
Identifiers
Old locus tagROSINTL182_08921RefSeq proteinWP_006859006.1
Context group ID
GCF_000156535::NZ_GG692748.1::G00015Context members
ROSINTL182_RS17455ROSINTL182_RS17460
Partner locus tags
ROSINTL182_RS17455ROSINTL182_RS17460
Partner old locus tags
ROSINTL182_08920ROSINTL182_08921
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_006859006.1Primary protein accession used for annex mappings.
UniProt accessionC7GG59Primary UniProt accession resolved in the annex database.
UniProt IDC7GG59_9FIRMDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagROSINTL182_RS17460Primary locus identifier stored in the genes table.
Old locus tagROSINTL182_08921Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG692748.1Sequence record reported by the local genomic context database.
Genomic interval17 357-18 793 nt1 437 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span16 656-18 793 ntGCF_000156535::NZ_GG692748.1::G00015
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000156535::NZ_GG692748.1::G00015Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG692748.1All displayed genes belong to this local TCS context.
Neighborhood span16 656-18 793 nt2 138 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
16 656 nt18 793 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
ROSINTL182_RS17455GCF_000156535#ROSINTL182_RS17455
RROmpR
16 656-17 360 nt · Forward (+)
ROSINTL182_RS17460GCF_000156535#ROSINTL182_RS17460
HKClassicCurrent focus
17 357-18 793 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000156535#ROSINTL182_RS17460The current gene is the representative for this cluster.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1636926
Simplified PFAM architecture for HKOC_1636926
PFAM domain coverage: 217 / 478 aa (45.4%)
1 aa478 aa
HAMPHisKAHATPase_c
- Simplified architecture: HAMP + HisKA + HATPase_c
- Raw architecture: HAMP[200-243] | HisKA[249-311] | HATPase_c[362-471]
- Domain count: 3
- Matched identifier: HKOC_1636926
- Positioned domains: HAMP 200-243 ; HisKA 249-311 ; HATPase_c 362-471
Cluster members and taxonomy
Representative gene: GCF_000156535#ROSINTL182_RS17460
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 536 231 · GCF_000156535
AssemblyASM15653v1 · Scaffoldhaploid
Genome composition4 411 375 bp · 42,5% GCRoseburia intestinalis L1-82
Signal transduction countsGenes 112 · HK 51 · RR 58CheA 1 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusRoseburia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Roseburia
Related genes
Preview from the same derived genome key