Gene detail

ROSINTL182_RS17265

Histidine kinase, Hybrid

Roseburia intestinalis L1-82 · GCF_000156535

ClassHKTypeHybridLength421 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000156535#ROSINTL182_RS17265Stable P2CS identifier used across views.
GenomeGCF_000156535Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Roseburia
Selected clusterHKOC_2256695Run 6 · 13 sequences · id 100% · cov 80% · representative
External referencesWP_006858962.1 · C7GG17 · MIST4 ROSINTL182_RS17265RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_cResponse_reg
Protein length421 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage300 / 421 aa (71.3%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_c,1 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa421 aa
HisKA: 43-108 aa (66 aa)1HATPase_c: 155-271 aa (117 aa)2Response_reg: 297-413 aa (117 aa)3
Domain-by-domain annotation3 items
1 HisKA#1
43-108 aa · 66 aa · 15.7% of protein
Raw tokenHisKA:43:0.000000000000106:108:66:64
2 HATPase_c#2
155-271 aa · 117 aa · 27.8% of protein
Raw tokenHATPase_c:155:9.05e-29:271:117:109
3 Response_reg#3
297-413 aa · 117 aa · 27.8% of protein
Raw tokenResponse_reg:297:8.01e-29:413:117:111
  • Raw architecture: HisKA:43:0.000000000000106:108:66:64#HATPase_c:155:9.05e-29:271:117:109#Response_reg:297:8.01e-29:413:117:111
  • Domain description: 1 HisKA,1 HATPase_c,1 Response_reg
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_000156535::NZ_GG692747.1::G00016
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span9318-10583Genomic interval covered by the local TCS group.
Identifiers
Old locus tagROSINTL182_08877RefSeq proteinWP_006858962.1
Context group IDGCF_000156535::NZ_GG692747.1::G00016
Context members
ROSINTL182_RS17265
Partner locus tags
ROSINTL182_RS17265
Partner old locus tags
ROSINTL182_08877
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_006858962.1Primary protein accession used for annex mappings.
UniProt accessionC7GG17Primary UniProt accession resolved in the annex database.
UniProt IDC7GG17_9FIRMDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagROSINTL182_RS17265Primary locus identifier stored in the genes table.
Old locus tagROSINTL182_08877Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG692747.1Sequence record reported by the local genomic context database.
Genomic interval9 318-10 583 nt1 266 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span9 318-10 583 ntGCF_000156535::NZ_GG692747.1::G00016

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000156535::NZ_GG692747.1::G00016

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG692747.1All displayed genes belong to this local TCS context.
Neighborhood span9 318-10 583 nt1 266 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
9 318 nt10 583 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2256695Run 6 · HK · 13 sequences
Representative sequenceGCF_000156535#ROSINTL182_RS17265The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c + Response_reg3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2256695

Simplified PFAM architecture for HKOC_2256695

PFAM domain coverage: 297 / 421 aa (70.5%)

1 aa421 aa
HisKA: 43-108 aaHisKAHATPase_c: 155-269 aaHATPase_cResponse_reg: 297-412 aaResponse_reg
HisKAHATPase_cResponse_reg
  • Simplified architecture: HisKA + HATPase_c + Response_reg
  • Raw architecture: HisKA[43-108] | HATPase_c[155-269] | Response_reg[297-412]
  • Domain count: 3
  • Matched identifier: HKOC_2256695
  • Positioned domains: HisKA 43-108 ; HATPase_c 155-269 ; Response_reg 297-412
Cluster members and taxonomy
Visualization

Representative gene: GCF_000156535#ROSINTL182_RS17265

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 536 231 · GCF_000156535
AssemblyASM15653v1 · Scaffoldhaploid
Genome composition4 411 375 bp · 42,5% GCRoseburia intestinalis L1-82
Signal transduction countsGenes 112 · HK 51 · RR 58CheA 1 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusRoseburia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Roseburia

Related genes

Preview from the same derived genome key