Gene detail

ROSINTL182_RS16130

Histidine kinase, Hybrid

Roseburia intestinalis L1-82 · GCF_000156535

ClassHKTypeHybridLength669 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000156535#ROSINTL182_RS16130Stable P2CS identifier used across views.
GenomeGCF_000156535Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Roseburia
Selected clusterHKOC_0480671Run 6 · 3 sequences · id 100% · cov 80%
External referencesWP_242655630.1 · MIST4 ROSINTL182_RS16130RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_cResponse_reg
Protein length669 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage300 / 669 aa (44.8%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_c,1 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa669 aa
HisKA: 281-347 aa (67 aa)1HATPase_c: 394-509 aa (116 aa)2Response_reg: 536-652 aa (117 aa)3
Domain-by-domain annotation3 items
1 HisKA#1
281-347 aa · 67 aa · 10.0% of protein
Raw tokenHisKA:281:0.00000000000000215:347:67:64
2 HATPase_c#2
394-509 aa · 116 aa · 17.3% of protein
Raw tokenHATPase_c:394:3.05e-30:509:117:109
3 Response_reg#3
536-652 aa · 117 aa · 17.5% of protein
Raw tokenResponse_reg:536:9.57e-28:652:117:111
  • Raw architecture: HisKA:281:0.00000000000000215:347:67:64#HATPase_c:394:3.05e-30:509:117:109#Response_reg:536:9.57e-28:652:117:111
  • Domain description: 1 HisKA,1 HATPase_c,1 Response_reg
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_000156535::NZ_GG692741.1::G00021
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span18759-20768Genomic interval covered by the local TCS group.
Identifiers
Old locus tagROSINTL182_08625RefSeq proteinWP_242655630.1
Context group IDGCF_000156535::NZ_GG692741.1::G00021
Context members
ROSINTL182_RS16130
Partner locus tags
ROSINTL182_RS16130
Partner old locus tags
ROSINTL182_08625
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_242655630.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagROSINTL182_RS16130Primary locus identifier stored in the genes table.
Old locus tagROSINTL182_08625Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG692741.1Sequence record reported by the local genomic context database.
Genomic interval18 759-20 768 nt2 010 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span18 759-20 768 ntGCF_000156535::NZ_GG692741.1::G00021

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000156535::NZ_GG692741.1::G00021

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG692741.1All displayed genes belong to this local TCS context.
Neighborhood span18 759-20 768 nt2 010 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
18 759 nt20 768 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0480671Run 6 · HK · 3 sequences
Representative sequenceGCF_015555785#I2G12_RS14490Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c + Response_reg3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0480671

Simplified PFAM architecture for HKOC_0480671

PFAM domain coverage: 298 / 855 aa (34.9%)

1 aa855 aa
HisKA: 467-533 aaHisKAHATPase_c: 582-695 aaHATPase_cResponse_reg: 722-838 aaResponse_reg
HisKAHATPase_cResponse_reg
  • Simplified architecture: HisKA + HATPase_c + Response_reg
  • Raw architecture: HisKA[467-533] | HATPase_c[582-695] | Response_reg[722-838]
  • Domain count: 3
  • Matched identifier: HKOC_0480671
  • Positioned domains: HisKA 467-533 ; HATPase_c 582-695 ; Response_reg 722-838
Cluster members and taxonomy
Visualization

Representative gene: GCF_015555785#I2G12_RS14490

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 536 231 · GCF_000156535
AssemblyASM15653v1 · Scaffoldhaploid
Genome composition4 411 375 bp · 42,5% GCRoseburia intestinalis L1-82
Signal transduction countsGenes 112 · HK 51 · RR 58CheA 1 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusRoseburia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Roseburia

Related genes

Preview from the same derived genome key