1 HAMP#1
152-222 aa · 71 aa · 15.5% of protein
Raw token
HAMP:152:0.0000106:222:71:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
ROSINTL182_RS14975
Histidine kinase, Classic
Roseburia intestinalis L1-82 · GCF_000156535
ClassHKTypeClassicLength458 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000156535#ROSINTL182_RS14975Stable P2CS identifier used across views.
GenomeGCF_000156535Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Roseburia
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length458 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage239 / 458 aa (52.2%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa458 aa
Domain-by-domain annotation3 items
2 HisKA#2
233-294 aa · 62 aa · 13.5% of protein
Raw token
HisKA:233:0.000000000013:294:62:643 HATPase_c#3
346-451 aa · 106 aa · 23.1% of protein
Raw token
HATPase_c:346:1.78e-17:451:106:109- Raw architecture: HAMP:152:0.0000106:222:71:69#HisKA:233:0.000000000013:294:62:64#HATPase_c:346:1.78e-17:451:106:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000156535::NZ_GG692736.1::G00025
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span23317-25343Genomic interval covered by the local TCS group.
Identifiers
Old locus tagROSINTL182_08364RefSeq proteinWP_006858443.1
Context group ID
GCF_000156535::NZ_GG692736.1::G00025Context members
ROSINTL182_RS14975ROSINTL182_RS14980
Partner locus tags
ROSINTL182_RS14975ROSINTL182_RS14980
Partner old locus tags
ROSINTL182_08364ROSINTL182_08365
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_006858443.1Primary protein accession used for annex mappings.
UniProt accessionC7GEL2Primary UniProt accession resolved in the annex database.
UniProt IDC7GEL2_9FIRMDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagROSINTL182_RS14975Primary locus identifier stored in the genes table.
Old locus tagROSINTL182_08364Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG692736.1Sequence record reported by the local genomic context database.
Genomic interval23 317-24 693 nt1 377 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span23 317-25 343 ntGCF_000156535::NZ_GG692736.1::G00025
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000156535::NZ_GG692736.1::G00025Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG692736.1All displayed genes belong to this local TCS context.
Neighborhood span23 317-25 343 nt2 027 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
23 317 nt25 343 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
ROSINTL182_RS14975GCF_000156535#ROSINTL182_RS14975
HKClassicCurrent focus
23 317-24 693 nt · Reverse (-)
ROSINTL182_RS14980GCF_000156535#ROSINTL182_RS14980
RROmpR
24 681-25 343 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000156535#ROSINTL182_RS14975The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1858394
Simplified PFAM architecture for HKOC_1858394
PFAM domain coverage: 166 / 458 aa (36.2%)
1 aa458 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[234-294] | HATPase_c[347-451]
- Domain count: 2
- Matched identifier: HKOC_1858394
- Positioned domains: HisKA 234-294 ; HATPase_c 347-451
Cluster members and taxonomy
Representative gene: GCF_000156535#ROSINTL182_RS14975
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 536 231 · GCF_000156535
AssemblyASM15653v1 · Scaffoldhaploid
Genome composition4 411 375 bp · 42,5% GCRoseburia intestinalis L1-82
Signal transduction countsGenes 112 · HK 51 · RR 58CheA 1 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusRoseburia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Roseburia
Related genes
Preview from the same derived genome key