1 HAMP#1
292-361 aa · 70 aa · 11.7% of protein
Raw token
HAMP:292:0.00000111:361:70:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
ROSINTL182_RS14240
Histidine kinase, Classic
Roseburia intestinalis L1-82 · GCF_000156535
ClassHKTypeClassicLength599 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000156535#ROSINTL182_RS14240Stable P2CS identifier used across views.
GenomeGCF_000156535Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Roseburia
Domain signature
Compact overview inferred from the domain field
HAMPHis_kinaseHATPase_c
Protein length599 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage252 / 599 aa (42.1%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa599 aa
Domain-by-domain annotation3 items
2 His_kinase#2
390-469 aa · 80 aa · 13.4% of protein
Raw token
His_kinase:390:9.01e-30:469:80:803 HATPase_c#3
494-595 aa · 102 aa · 17.0% of protein
Raw token
HATPase_c:494:0.0000000000982:595:102:109- Raw architecture: HAMP:292:0.00000111:361:70:69#His_kinase:390:9.01e-30:469:80:80#HATPase_c:494:0.0000000000982:595:102:109
- Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000156535::NZ_GG692733.1::G00030
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span45612-49060Genomic interval covered by the local TCS group.
Identifiers
Old locus tagROSINTL182_08201RefSeq proteinWP_006858282.1
Context group ID
GCF_000156535::NZ_GG692733.1::G00030Context members
ROSINTL182_RS14235ROSINTL182_RS14240
Partner locus tags
ROSINTL182_RS14235ROSINTL182_RS14240
Partner old locus tags
ROSINTL182_08200ROSINTL182_08201
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_006858282.1Primary protein accession used for annex mappings.
UniProt accessionC7GE49Primary UniProt accession resolved in the annex database.
UniProt IDC7GE49_9FIRMDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagROSINTL182_RS14240Primary locus identifier stored in the genes table.
Old locus tagROSINTL182_08201Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG692733.1Sequence record reported by the local genomic context database.
Genomic interval47 261-49 060 nt1 800 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span45 612-49 060 ntGCF_000156535::NZ_GG692733.1::G00030
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000156535::NZ_GG692733.1::G00030Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG692733.1All displayed genes belong to this local TCS context.
Neighborhood span45 612-49 060 nt3 449 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
45 612 nt49 060 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
ROSINTL182_RS14235GCF_000156535#ROSINTL182_RS14235
RRunclassified
45 612-47 210 nt · Reverse (-)
ROSINTL182_RS14240GCF_000156535#ROSINTL182_RS14240
HKClassicCurrent focus
47 261-49 060 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000156535#ROSINTL182_RS14240The current gene is the representative for this cluster.
PFAM architectureHis_kinase + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1057261
Simplified PFAM architecture for HKOC_1057261
PFAM domain coverage: 183 / 599 aa (30.6%)
1 aa599 aa
His_kinaseHATPase_c
- Simplified architecture: His_kinase + HATPase_c
- Raw architecture: His_kinase[390-469] | HATPase_c[494-596]
- Domain count: 2
- Matched identifier: HKOC_1057261
- Positioned domains: His_kinase 390-469 ; HATPase_c 494-596
Cluster members and taxonomy
Representative gene: GCF_000156535#ROSINTL182_RS14240
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 536 231 · GCF_000156535
AssemblyASM15653v1 · Scaffoldhaploid
Genome composition4 411 375 bp · 42,5% GCRoseburia intestinalis L1-82
Signal transduction countsGenes 112 · HK 51 · RR 58CheA 1 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusRoseburia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Roseburia
Related genes
Preview from the same derived genome key