1 HAMP#1
280-344 aa · 65 aa · 11.3% of protein
Raw token
HAMP:280:0.0000000824:344:65:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
ROSINTL182_RS11580
Histidine kinase, Classic
Roseburia intestinalis L1-82 · GCF_000156535
ClassHKTypeClassicLength573 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000156535#ROSINTL182_RS11580Stable P2CS identifier used across views.
GenomeGCF_000156535Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Roseburia
Domain signature
Compact overview inferred from the domain field
HAMPHis_kinaseHATPase_c
Protein length573 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage259 / 573 aa (45.2%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa573 aa
Domain-by-domain annotation3 items
2 His_kinase#2
367-445 aa · 79 aa · 13.8% of protein
Raw token
His_kinase:367:2.14e-28:445:79:803 HATPase_c#3
453-567 aa · 115 aa · 20.1% of protein
Raw token
HATPase_c:453:0.000000000000337:567:124:109- Raw architecture: HAMP:280:0.0000000824:344:65:69#His_kinase:367:2.14e-28:445:79:80#HATPase_c:453:0.000000000000337:567:124:109
- Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelorphanGCF_000156535::NZ_GG692726.1::G00040
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span87821-89542Genomic interval covered by the local TCS group.
Identifiers
Old locus tagROSINTL182_07605RefSeq proteinWP_242655581.1
Context group ID
GCF_000156535::NZ_GG692726.1::G00040Context members
ROSINTL182_RS11580
Partner locus tags
ROSINTL182_RS11580
Partner old locus tags
ROSINTL182_07605
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_242655581.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagROSINTL182_RS11580Primary locus identifier stored in the genes table.
Old locus tagROSINTL182_07605Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG692726.1Sequence record reported by the local genomic context database.
Genomic interval87 821-89 542 nt1 722 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span87 821-89 542 ntGCF_000156535::NZ_GG692726.1::G00040
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000156535::NZ_GG692726.1::G00040Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG692726.1All displayed genes belong to this local TCS context.
Neighborhood span87 821-89 542 nt1 722 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
87 821 nt89 542 nt
Neighborhood gene cards
1 gene in the current local neighborhood.
ROSINTL182_RS11580GCF_000156535#ROSINTL182_RS11580
HKClassicCurrent focus
87 821-89 542 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_025151715#NQ522_RS08875Use this link to inspect the representative gene detail.
PFAM architectureHis_kinase + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1102579
Simplified PFAM architecture for HKOC_1102579
PFAM domain coverage: 182 / 592 aa (30.7%)
1 aa592 aa
His_kinaseHATPase_c
- Simplified architecture: His_kinase + HATPase_c
- Raw architecture: His_kinase[386-464] | HATPase_c[484-586]
- Domain count: 2
- Matched identifier: HKOC_1102579
- Positioned domains: His_kinase 386-464 ; HATPase_c 484-586
Cluster members and taxonomy
Representative gene: GCF_025151715#NQ522_RS08875
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 536 231 · GCF_000156535
AssemblyASM15653v1 · Scaffoldhaploid
Genome composition4 411 375 bp · 42,5% GCRoseburia intestinalis L1-82
Signal transduction countsGenes 112 · HK 51 · RR 58CheA 1 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusRoseburia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Roseburia
Related genes
Preview from the same derived genome key