Gene detail

ROSINTL182_RS11110

Histidine kinase, Classic

Roseburia intestinalis L1-82 · GCF_000156535

ClassHKTypeClassicLength444 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000156535#ROSINTL182_RS11110Stable P2CS identifier used across views.
GenomeGCF_000156535Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Roseburia
Selected clusterHKOC_2032167Run 6 · 52 sequences · id 100% · cov 80% · representative
External referencesWP_006857577.1 · A0AAW4W5E2 · MIST4 ROSINTL182_RS11110RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length444 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage238 / 444 aa (53.6%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa444 aa
HAMP: 138-202 aa (65 aa)1HisKA: 219-288 aa (70 aa)2HATPase_c: 337-439 aa (103 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
138-202 aa · 65 aa · 14.6% of protein
Raw tokenHAMP:138:0.00000000405:202:65:69
2 HisKA#2
219-288 aa · 70 aa · 15.8% of protein
Raw tokenHisKA:219:0.000000000759:288:70:64
3 HATPase_c#3
337-439 aa · 103 aa · 23.2% of protein
Raw tokenHATPase_c:337:3.38e-23:439:104:109
  • Raw architecture: HAMP:138:0.00000000405:202:65:69#HisKA:219:0.000000000759:288:70:64#HATPase_c:337:3.38e-23:439:104:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000156535::NZ_GG692725.1::G00043
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span114613-116609Genomic interval covered by the local TCS group.
Identifiers
Old locus tagROSINTL182_07498RefSeq proteinWP_006857577.1
Context group IDGCF_000156535::NZ_GG692725.1::G00043
Context members
ROSINTL182_RS11110ROSINTL182_RS11115
Partner locus tags
ROSINTL182_RS11110ROSINTL182_RS11115
Partner old locus tags
ROSINTL182_07498ROSINTL182_07499
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_006857577.1Primary protein accession used for annex mappings.
UniProt accessionA0AAW4W5E2Primary UniProt accession resolved in the annex database.
UniProt IDA0AAW4W5E2_9FIRMDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagROSINTL182_RS11110Primary locus identifier stored in the genes table.
Old locus tagROSINTL182_07498Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG692725.1Sequence record reported by the local genomic context database.
Genomic interval114 613-115 947 nt1 335 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span114 613-116 609 ntGCF_000156535::NZ_GG692725.1::G00043

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000156535::NZ_GG692725.1::G00043

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG692725.1All displayed genes belong to this local TCS context.
Neighborhood span114 613-116 609 nt1 997 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
114 613 nt116 609 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

ROSINTL182_RS11115GCF_000156535#ROSINTL182_RS11115
RROmpR

115 935-116 609 nt · Reverse (-)

Old locus ROSINTL182_07499RefSeq WP_020994080.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2032167Run 6 · HK · 52 sequences
Representative sequenceGCF_000156535#ROSINTL182_RS11110The current gene is the representative for this cluster.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2032167

Simplified PFAM architecture for HKOC_2032167

PFAM domain coverage: 216 / 444 aa (48.6%)

1 aa444 aa
HAMP: 156-202 aaHAMPHisKA: 220-287 aaHisKAHATPase_c: 337-437 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[156-202] | HisKA[220-287] | HATPase_c[337-437]
  • Domain count: 3
  • Matched identifier: HKOC_2032167
  • Positioned domains: HAMP 156-202 ; HisKA 220-287 ; HATPase_c 337-437
Cluster members and taxonomy
Visualization

Representative gene: GCF_000156535#ROSINTL182_RS11110

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 536 231 · GCF_000156535
AssemblyASM15653v1 · Scaffoldhaploid
Genome composition4 411 375 bp · 42,5% GCRoseburia intestinalis L1-82
Signal transduction countsGenes 112 · HK 51 · RR 58CheA 1 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusRoseburia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Roseburia

Related genes

Preview from the same derived genome key