1 Response_reg#1
5-108 aa · 104 aa · 29.4% of protein
Raw token
Response_reg:5:1.74e-25:108:104:111P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
ROSINTL182_RS10535
Response regulator, CheB family
Roseburia intestinalis L1-82 · GCF_000156535
ClassRRTypeCheBLength354 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000156535#ROSINTL182_RS10535Stable P2CS identifier used across views.
GenomeGCF_000156535Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Roseburia
Domain signature
Compact overview inferred from the domain field
Response_regCheB_methylest
Protein length354 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage287 / 354 aa (81.1%)Merged over positioned domains only.
Domain description1 Response_reg,1 CheB_methylestSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa354 aa
Domain-by-domain annotation2 items
2 CheB_methylest#2
165-347 aa · 183 aa · 51.7% of protein
Raw token
CheB_methylest:165:2.35e-79:347:183:177- Raw architecture: Response_reg:5:1.74e-25:108:104:111#CheB_methylest:165:2.35e-79:347:183:177
- Domain description: 1 Response_reg,1 CheB_methylest
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000156535::NZ_GG692725.1::G00041
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span15307-18487Genomic interval covered by the local TCS group.
Identifiers
Old locus tagROSINTL182_07370RefSeq proteinWP_006857473.1
Context group ID
GCF_000156535::NZ_GG692725.1::G00041Context members
ROSINTL182_RS10530ROSINTL182_RS10535
Partner locus tags
ROSINTL182_RS10530ROSINTL182_RS10535
Partner old locus tags
ROSINTL182_07369ROSINTL182_07370
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_006857473.1Primary protein accession used for annex mappings.
UniProt accessionD4KW89Primary UniProt accession resolved in the annex database.
UniProt IDD4KW89_9FIRMDisplay identifier provided by UniProt.
GO / PubMed5 / 0Unique GO terms and literature references available below.
Reference hubs
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagROSINTL182_RS10535Primary locus identifier stored in the genes table.
Old locus tagROSINTL182_07370Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG692725.1Sequence record reported by the local genomic context database.
Genomic interval17 423-18 487 nt1 065 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span15 307-18 487 ntGCF_000156535::NZ_GG692725.1::G00041
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000156535::NZ_GG692725.1::G00041Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG692725.1All displayed genes belong to this local TCS context.
Neighborhood span15 307-18 487 nt3 181 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
15 307 nt18 487 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
ROSINTL182_RS10530GCF_000156535#ROSINTL182_RS10530
HKCheA
15 307-17 421 nt · Reverse (-)
ROSINTL182_RS10535GCF_000156535#ROSINTL182_RS10535
RRCheBCurrent focus
17 423-18 487 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000156535#ROSINTL182_RS10535The current gene is the representative for this cluster.
PFAM architectureResponse_reg + CheB_methylest2 domains in the representative PFAM annotation.
PFAM architecture for RROC_0471149
Simplified PFAM architecture for RROC_0471149
PFAM domain coverage: 289 / 354 aa (81.6%)
1 aa354 aa
Response_regCheB_methylest
- Simplified architecture: Response_reg + CheB_methylest
- Raw architecture: Response_reg[5-110] | CheB_methylest[165-347]
- Domain count: 2
- Matched identifier: RROC_0471149
- Positioned domains: Response_reg 5-110 ; Response_reg 5-110 ; CheB_methylest 165-347 ; CheB_methylest 165-347
Cluster members and taxonomy
Representative gene: GCF_000156535#ROSINTL182_RS10535
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 536 231 · GCF_000156535
AssemblyASM15653v1 · Scaffoldhaploid
Genome composition4 411 375 bp · 42,5% GCRoseburia intestinalis L1-82
Signal transduction countsGenes 112 · HK 51 · RR 58CheA 1 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusRoseburia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Roseburia
Related genes
Preview from the same derived genome key