1 Hpt#1
5-98 aa · 94 aa · 13.4% of protein
Raw token
Hpt:5:1.36e-16:98:94:84P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
ROSINTL182_RS10530
Histidine kinase, CheA
Roseburia intestinalis L1-82 · GCF_000156535
ClassHKTypeCheALength704 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000156535#ROSINTL182_RS10530Stable P2CS identifier used across views.
GenomeGCF_000156535Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Roseburia
Domain signature
Compact overview inferred from the domain field
HptH-kinase_dimHATPase_cCheW
Protein length704 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage425 / 704 aa (60.4%)Merged over positioned domains only.
Domain description1 Hpt,1 H-kinase_dim,1 HATPase_c,1 CheWSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa704 aa
Domain-by-domain annotation4 items
2 H-kinase_dim#2
323-386 aa · 64 aa · 9.1% of protein
Raw token
H-kinase_dim:323:0.00000000000000317:386:67:673 HATPase_c#3
434-573 aa · 140 aa · 19.9% of protein
Raw token
HATPase_c:434:0.00000000000000282:573:140:1094 CheW#4
578-704 aa · 127 aa · 18.0% of protein
Raw token
CheW:578:1.61e-31:704:134:138- Raw architecture: Hpt:5:1.36e-16:98:94:84#H-kinase_dim:323:0.00000000000000317:386:67:67#HATPase_c:434:0.00000000000000282:573:140:109#CheW:578:1.61e-31:704:134:138
- Domain description: 1 Hpt,1 H-kinase_dim,1 HATPase_c,1 CheW
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000156535::NZ_GG692725.1::G00041
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span15307-18487Genomic interval covered by the local TCS group.
Identifiers
Old locus tagROSINTL182_07369RefSeq proteinWP_015520447.1
Context group ID
GCF_000156535::NZ_GG692725.1::G00041Context members
ROSINTL182_RS10530ROSINTL182_RS10535
Partner locus tags
ROSINTL182_RS10530ROSINTL182_RS10535
Partner old locus tags
ROSINTL182_07369ROSINTL182_07370
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_015520447.1Primary protein accession used for annex mappings.
UniProt accessionD4KW90Primary UniProt accession resolved in the annex database.
UniProt IDD4KW90_9FIRMDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.
Reference hubs
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagROSINTL182_RS10530Primary locus identifier stored in the genes table.
Old locus tagROSINTL182_07369Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG692725.1Sequence record reported by the local genomic context database.
Genomic interval15 307-17 421 nt2 115 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span15 307-18 487 ntGCF_000156535::NZ_GG692725.1::G00041
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000156535::NZ_GG692725.1::G00041Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG692725.1All displayed genes belong to this local TCS context.
Neighborhood span15 307-18 487 nt3 181 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
15 307 nt18 487 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
ROSINTL182_RS10530GCF_000156535#ROSINTL182_RS10530
HKCheACurrent focus
15 307-17 421 nt · Reverse (-)
ROSINTL182_RS10535GCF_000156535#ROSINTL182_RS10535
RRCheB
17 423-18 487 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000156535#ROSINTL182_RS10530The current gene is the representative for this cluster.
PFAM architectureHpt + P2 + H-kinase_dim + HATPase_c + CheW5 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0760735
Simplified PFAM architecture for HKOC_0760735
PFAM domain coverage: 501 / 704 aa (71.2%)
1 aa704 aa
HptP2H-kinase_dimHATPase_cCheW
- Simplified architecture: Hpt + P2 + H-kinase_dim + HATPase_c + CheW
- Raw architecture: Hpt[5-98] | P2[181-257] | H-kinase_dim[322-386] | HATPase_c[435-573] | CheW[578-703]
- Domain count: 5
- Matched identifier: HKOC_0760735
- Positioned domains: Hpt 5-98 ; P2 181-257 ; H-kinase_dim 322-386 ; HATPase_c 435-573 ; CheW 578-703
Cluster members and taxonomy
Representative gene: GCF_000156535#ROSINTL182_RS10530
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 536 231 · GCF_000156535
AssemblyASM15653v1 · Scaffoldhaploid
Genome composition4 411 375 bp · 42,5% GCRoseburia intestinalis L1-82
Signal transduction countsGenes 112 · HK 51 · RR 58CheA 1 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusRoseburia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Roseburia
Related genes
Preview from the same derived genome key