1 His_kinase#1
365-443 aa · 79 aa · 13.7% of protein
Raw token
His_kinase:365:2.44e-22:443:79:80P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
ROSINTL182_RS10355
Histidine kinase, Classic
Roseburia intestinalis L1-82 · GCF_000156535
ClassHKTypeClassicLength576 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000156535#ROSINTL182_RS10355Stable P2CS identifier used across views.
GenomeGCF_000156535Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Roseburia
Domain signature
Compact overview inferred from the domain field
His_kinaseHATPase_c
Protein length576 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage182 / 576 aa (31.6%)Merged over positioned domains only.
Domain description1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa576 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
467-569 aa · 103 aa · 17.9% of protein
Raw token
HATPase_c:467:0.0000000406:569:107:109- Raw architecture: His_kinase:365:2.44e-22:443:79:80#HATPase_c:467:0.0000000406:569:107:109
- Domain description: 1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000156535::NZ_GG692724.1::G00045
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span107099-110430Genomic interval covered by the local TCS group.
Identifiers
Old locus tagROSINTL182_07329RefSeq proteinWP_157579700.1
Context group ID
GCF_000156535::NZ_GG692724.1::G00045Context members
ROSINTL182_RS10350ROSINTL182_RS10355
Partner locus tags
ROSINTL182_RS10350ROSINTL182_RS10355
Partner old locus tags
ROSINTL182_07328ROSINTL182_07329
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_157579700.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagROSINTL182_RS10355Primary locus identifier stored in the genes table.
Old locus tagROSINTL182_07329Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG692724.1Sequence record reported by the local genomic context database.
Genomic interval108 700-110 430 nt1 731 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span107 099-110 430 ntGCF_000156535::NZ_GG692724.1::G00045
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000156535::NZ_GG692724.1::G00045Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG692724.1All displayed genes belong to this local TCS context.
Neighborhood span107 099-110 430 nt3 332 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
107 099 nt110 430 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
ROSINTL182_RS10350GCF_000156535#ROSINTL182_RS10350
RRunclassified
107 099-108 703 nt · Reverse (-)
ROSINTL182_RS10355GCF_000156535#ROSINTL182_RS10355
HKClassicCurrent focus
108 700-110 430 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000156535#ROSINTL182_RS10355The current gene is the representative for this cluster.
PFAM architectureHis_kinase + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1182908
Simplified PFAM architecture for HKOC_1182908
PFAM domain coverage: 185 / 576 aa (32.1%)
1 aa576 aa
His_kinaseHATPase_c
- Simplified architecture: His_kinase + HATPase_c
- Raw architecture: His_kinase[365-443] | HATPase_c[463-568]
- Domain count: 2
- Matched identifier: HKOC_1182908
- Positioned domains: His_kinase 365-443 ; HATPase_c 463-568
Cluster members and taxonomy
Representative gene: GCF_000156535#ROSINTL182_RS10355
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 536 231 · GCF_000156535
AssemblyASM15653v1 · Scaffoldhaploid
Genome composition4 411 375 bp · 42,5% GCRoseburia intestinalis L1-82
Signal transduction countsGenes 112 · HK 51 · RR 58CheA 1 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusRoseburia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Roseburia
Related genes
Preview from the same derived genome key