Gene detail

ROSINTL182_RS10335

Histidine kinase, Unorthodox

Roseburia intestinalis L1-82 · GCF_000156535

ClassHKTypeUnorthodoxLength867 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000156535#ROSINTL182_RS10335Stable P2CS identifier used across views.
GenomeGCF_000156535Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Roseburia
Selected clusterHKOC_0462115Run 6 · 2 sequences · id 100% · cov 80% · representative
External referencesWP_006857412.1 · C7GBP0 · MIST4 ROSINTL182_RS10335RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_cResponse_regHpt
Protein length867 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage379 / 867 aa (43.7%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_c,1 Response_reg,1 HptSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa867 aa
HisKA: 266-331 aa (66 aa)1HATPase_c: 378-494 aa (117 aa)2Response_reg: 528-642 aa (115 aa)3Hpt: 699-779 aa (81 aa)4
Domain-by-domain annotation4 items
1 HisKA#1
266-331 aa · 66 aa · 7.6% of protein
Raw tokenHisKA:266:7.01e-17:331:66:64
2 HATPase_c#2
378-494 aa · 117 aa · 13.5% of protein
Raw tokenHATPase_c:378:1.93e-29:494:117:109
3 Response_reg#3
528-642 aa · 115 aa · 13.3% of protein
Raw tokenResponse_reg:528:5.67e-30:642:115:111
4 Hpt#4
699-779 aa · 81 aa · 9.3% of protein
Raw tokenHpt:699:0.0000000672:779:81:84
  • Raw architecture: HisKA:266:7.01e-17:331:66:64#HATPase_c:378:1.93e-29:494:117:109#Response_reg:528:5.67e-30:642:115:111#Hpt:699:0.0000000672:779:81:84
  • Domain description: 1 HisKA,1 HATPase_c,1 Response_reg,1 Hpt
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000156535::NZ_GG692724.1::G00044
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span101010-104188Genomic interval covered by the local TCS group.
Identifiers
Old locus tagROSINTL182_07325RefSeq proteinWP_006857412.1
Context group IDGCF_000156535::NZ_GG692724.1::G00044
Context members
ROSINTL182_RS10330ROSINTL182_RS10335
Partner locus tags
ROSINTL182_RS10330ROSINTL182_RS10335
Partner old locus tags
ROSINTL182_07324ROSINTL182_07325
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_006857412.1Primary protein accession used for annex mappings.
UniProt accessionC7GBP0Primary UniProt accession resolved in the annex database.
UniProt IDC7GBP0_9FIRMDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagROSINTL182_RS10335Primary locus identifier stored in the genes table.
Old locus tagROSINTL182_07325Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG692724.1Sequence record reported by the local genomic context database.
Genomic interval101 585-104 188 nt2 604 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span101 010-104 188 ntGCF_000156535::NZ_GG692724.1::G00044

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000156535::NZ_GG692724.1::G00044

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG692724.1All displayed genes belong to this local TCS context.
Neighborhood span101 010-104 188 nt3 179 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
101 010 nt104 188 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

ROSINTL182_RS10330GCF_000156535#ROSINTL182_RS10330
RRunclassified

101 010-101 690 nt · Reverse (-)

Old locus ROSINTL182_07324RefSeq WP_134523452.1
ROSINTL182_RS10335GCF_000156535#ROSINTL182_RS10335
HKUnorthodoxCurrent focus

101 585-104 188 nt · Reverse (-)

Old locus ROSINTL182_07325RefSeq WP_006857412.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0462115Run 6 · HK · 2 sequences
Representative sequenceGCF_000156535#ROSINTL182_RS10335The current gene is the representative for this cluster.
PFAM architectureHisKA_7TM + HisKA + HATPase_c + Response_reg + Hpt5 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0462115

Simplified PFAM architecture for HKOC_0462115

PFAM domain coverage: 516 / 867 aa (59.5%)

1 aa867 aa
HisKA_7TM: 8-150 aaHisKA_7TMHisKA: 266-331 aaHisKAHATPase_c: 379-492 aaHATPase_cResponse_reg: 528-641 aaResponse_regHpt: 700-778 aaHpt
HisKA_7TMHisKAHATPase_cResponse_regHpt
  • Simplified architecture: HisKA_7TM + HisKA + HATPase_c + Response_reg + Hpt
  • Raw architecture: HisKA_7TM[8-150] | HisKA[266-331] | HATPase_c[379-492] | Response_reg[528-641] | Hpt[700-778]
  • Domain count: 5
  • Matched identifier: HKOC_0462115
  • Positioned domains: HisKA_7TM 8-150 ; HisKA 266-331 ; HATPase_c 379-492 ; Response_reg 528-641 ; Hpt 700-778
Cluster members and taxonomy
Visualization

Representative gene: GCF_000156535#ROSINTL182_RS10335

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 536 231 · GCF_000156535
AssemblyASM15653v1 · Scaffoldhaploid
Genome composition4 411 375 bp · 42,5% GCRoseburia intestinalis L1-82
Signal transduction countsGenes 112 · HK 51 · RR 58CheA 1 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusRoseburia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Roseburia

Related genes

Preview from the same derived genome key