Gene detail

ROSINTL182_RS09265

Histidine kinase, Unorthodox

Roseburia intestinalis L1-82 · GCF_000156535

ClassHKTypeUnorthodoxLength898 aaTM0ValidatedNoCompleteYesContexttriad
Gene IDGCF_000156535#ROSINTL182_RS09265Stable P2CS identifier used across views.
GenomeGCF_000156535Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Roseburia
Selected clusterHKOC_0408848Run 6 · 3 sequences · id 100% · cov 80% · representative
External referencesWP_242655565.1 · A0AAQ2UBL9 · MIST4 ROSINTL182_RS09265RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_cResponse_regHpt
Protein length898 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage357 / 898 aa (39.8%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_c,1 Response_reg,1 HptSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa898 aa
HisKA: 181-245 aa (65 aa)1HATPase_c: 293-405 aa (113 aa)2Response_reg: 561-675 aa (115 aa)3Hpt: 735-798 aa (64 aa)4
Domain-by-domain annotation4 items
1 HisKA#1
181-245 aa · 65 aa · 7.2% of protein
Raw tokenHisKA:181:0.0000000000000316:245:65:64
2 HATPase_c#2
293-405 aa · 113 aa · 12.6% of protein
Raw tokenHATPase_c:293:4.18e-25:405:113:109
3 Response_reg#3
561-675 aa · 115 aa · 12.8% of protein
Raw tokenResponse_reg:561:1.14e-20:675:115:111
4 Hpt#4
735-798 aa · 64 aa · 7.1% of protein
Raw tokenHpt:735:0.00000000497:798:64:84
  • Raw architecture: HisKA:181:0.0000000000000316:245:65:64#HATPase_c:293:4.18e-25:405:113:109#Response_reg:561:1.14e-20:675:115:111#Hpt:735:0.00000000497:798:64:84
  • Domain description: 1 HisKA,1 HATPase_c,1 Response_reg,1 Hpt
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labeltriadGCF_000156535::NZ_GG692723.1::G00046
Group size33 locus tags listed below.
HK / RR2 / 1Counts resolved for the local TCS neighborhood.
Context span5397-11825Genomic interval covered by the local TCS group.
Identifiers
Old locus tagROSINTL182_07087RefSeq proteinWP_242655565.1
Context group IDGCF_000156535::NZ_GG692723.1::G00046
Context members
ROSINTL182_RS09260ROSINTL182_RS09265ROSINTL182_RS09270
Partner locus tags
ROSINTL182_RS09260ROSINTL182_RS09265ROSINTL182_RS09270
Partner old locus tags
ROSINTL182_07086ROSINTL182_07087ROSINTL182_07088

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_242655565.1Primary protein accession used for annex mappings.
UniProt accessionA0AAQ2UBL9Primary UniProt accession resolved in the annex database.
UniProt IDA0AAQ2UBL9_9FIRMDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagROSINTL182_RS09265Primary locus identifier stored in the genes table.
Old locus tagROSINTL182_07087Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG692723.1Sequence record reported by the local genomic context database.
Genomic interval6 461-9 157 nt2 697 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span5 397-11 825 ntGCF_000156535::NZ_GG692723.1::G00046

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000156535::NZ_GG692723.1::G00046

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labeltriadNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG692723.1All displayed genes belong to this local TCS context.
Neighborhood span5 397-11 825 nt6 429 nt
Members31 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
5 397 nt11 825 nt
Neighborhood gene cards

3 genes in the current local neighborhood.

ROSINTL182_RS09260GCF_000156535#ROSINTL182_RS09260
RRRpfG

5 397-6 449 nt · Forward (+)

Old locus ROSINTL182_07086RefSeq WP_006857201.1
ROSINTL182_RS09270GCF_000156535#ROSINTL182_RS09270
HKHybrid

9 150-11 825 nt · Forward (+)

Old locus ROSINTL182_07088RefSeq WP_006857202.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0408848Run 6 · HK · 3 sequences
Representative sequenceGCF_000156535#ROSINTL182_RS09265The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c + Response_reg + Hpt4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0408848

Simplified PFAM architecture for HKOC_0408848

PFAM domain coverage: 354 / 898 aa (39.4%)

1 aa898 aa
HisKA: 181-245 aaHisKAHATPase_c: 293-406 aaHATPase_cResponse_reg: 561-672 aaResponse_regHpt: 735-797 aaHpt
HisKAHATPase_cResponse_regHpt
  • Simplified architecture: HisKA + HATPase_c + Response_reg + Hpt
  • Raw architecture: HisKA[181-245] | HATPase_c[293-406] | Response_reg[561-672] | Hpt[735-797]
  • Domain count: 4
  • Matched identifier: HKOC_0408848
  • Positioned domains: HisKA 181-245 ; HATPase_c 293-406 ; Response_reg 561-672 ; Hpt 735-797
Cluster members and taxonomy
Visualization

Representative gene: GCF_000156535#ROSINTL182_RS09265

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 536 231 · GCF_000156535
AssemblyASM15653v1 · Scaffoldhaploid
Genome composition4 411 375 bp · 42,5% GCRoseburia intestinalis L1-82
Signal transduction countsGenes 112 · HK 51 · RR 58CheA 1 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusRoseburia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Roseburia

Related genes

Preview from the same derived genome key