Gene detail

ROSINTL182_RS07855

Histidine kinase, Hybrid

Roseburia intestinalis L1-82 · GCF_000156535

ClassHKTypeHybridLength529 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000156535#ROSINTL182_RS07855Stable P2CS identifier used across views.
GenomeGCF_000156535Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Roseburia
Selected clusterHKOC_1359701Run 6 · 5 sequences · id 100% · cov 80% · representative
External referencesWP_006856857.1 · C7GA12 · MIST4 ROSINTL182_RS07855RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_cResponse_reg
Protein length529 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage301 / 529 aa (56.9%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_c,1 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa529 aa
HisKA: 150-216 aa (67 aa)1HATPase_c: 264-380 aa (117 aa)2Response_reg: 404-520 aa (117 aa)3
Domain-by-domain annotation3 items
1 HisKA#1
150-216 aa · 67 aa · 12.7% of protein
Raw tokenHisKA:150:0.00000000166:216:67:64
2 HATPase_c#2
264-380 aa · 117 aa · 22.1% of protein
Raw tokenHATPase_c:264:3.99e-26:380:117:109
3 Response_reg#3
404-520 aa · 117 aa · 22.1% of protein
Raw tokenResponse_reg:404:2.19e-27:520:117:111
  • Raw architecture: HisKA:150:0.00000000166:216:67:64#HATPase_c:264:3.99e-26:380:117:109#Response_reg:404:2.19e-27:520:117:111
  • Domain description: 1 HisKA,1 HATPase_c,1 Response_reg
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_000156535::NZ_GG692720.1::G00053
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span100413-102002Genomic interval covered by the local TCS group.
Identifiers
Old locus tagROSINTL182_06764RefSeq proteinWP_006856857.1
Context group IDGCF_000156535::NZ_GG692720.1::G00053
Context members
ROSINTL182_RS07855
Partner locus tags
ROSINTL182_RS07855
Partner old locus tags
ROSINTL182_06764
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_006856857.1Primary protein accession used for annex mappings.
UniProt accessionC7GA12Primary UniProt accession resolved in the annex database.
UniProt IDC7GA12_9FIRMDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagROSINTL182_RS07855Primary locus identifier stored in the genes table.
Old locus tagROSINTL182_06764Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG692720.1Sequence record reported by the local genomic context database.
Genomic interval100 413-102 002 nt1 590 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span100 413-102 002 ntGCF_000156535::NZ_GG692720.1::G00053

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000156535::NZ_GG692720.1::G00053

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG692720.1All displayed genes belong to this local TCS context.
Neighborhood span100 413-102 002 nt1 590 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
100 413 nt102 002 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1359701Run 6 · HK · 5 sequences
Representative sequenceGCF_000156535#ROSINTL182_RS07855The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c + Response_reg3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1359701

Simplified PFAM architecture for HKOC_1359701

PFAM domain coverage: 299 / 529 aa (56.5%)

1 aa529 aa
HisKA: 150-216 aaHisKAHATPase_c: 264-379 aaHATPase_cResponse_reg: 404-519 aaResponse_reg
HisKAHATPase_cResponse_reg
  • Simplified architecture: HisKA + HATPase_c + Response_reg
  • Raw architecture: HisKA[150-216] | HATPase_c[264-379] | Response_reg[404-519]
  • Domain count: 3
  • Matched identifier: HKOC_1359701
  • Positioned domains: HisKA 150-216 ; HATPase_c 264-379 ; Response_reg 404-519
Cluster members and taxonomy
Visualization

Representative gene: GCF_000156535#ROSINTL182_RS07855

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 536 231 · GCF_000156535
AssemblyASM15653v1 · Scaffoldhaploid
Genome composition4 411 375 bp · 42,5% GCRoseburia intestinalis L1-82
Signal transduction countsGenes 112 · HK 51 · RR 58CheA 1 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusRoseburia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Roseburia

Related genes

Preview from the same derived genome key