1 HAMP#1
187-253 aa · 67 aa · 13.3% of protein
Raw token
HAMP:187:0.0000000000496:253:68:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
ROSINTL182_RS07720
Histidine kinase, Classic
Roseburia intestinalis L1-82 · GCF_000156535
ClassHKTypeClassicLength505 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000156535#ROSINTL182_RS07720Stable P2CS identifier used across views.
GenomeGCF_000156535Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Roseburia
Domain signature
Compact overview inferred from the domain field
HAMPHis_kinaseHATPase_c
Protein length505 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage244 / 505 aa (48.3%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa505 aa
Domain-by-domain annotation3 items
2 His_kinase#2
291-370 aa · 80 aa · 15.8% of protein
Raw token
His_kinase:291:2.63e-36:370:80:803 HATPase_c#3
393-489 aa · 97 aa · 19.2% of protein
Raw token
HATPase_c:393:0.0000000000338:489:102:109- Raw architecture: HAMP:187:0.0000000000496:253:68:69#His_kinase:291:2.63e-36:370:80:80#HATPase_c:393:0.0000000000338:489:102:109
- Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000156535::NZ_GG692720.1::G00052
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span72645-74961Genomic interval covered by the local TCS group.
Identifiers
Old locus tagROSINTL182_06732RefSeq proteinWP_242655549.1
Context group ID
GCF_000156535::NZ_GG692720.1::G00052Context members
ROSINTL182_RS07720ROSINTL182_RS07725
Partner locus tags
ROSINTL182_RS07720ROSINTL182_RS07725
Partner old locus tags
ROSINTL182_06732ROSINTL182_06733
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_242655549.1Primary protein accession used for annex mappings.
UniProt accessionA0AAQ2UEZ4Primary UniProt accession resolved in the annex database.
UniProt IDA0AAQ2UEZ4_9FIRMDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagROSINTL182_RS07720Primary locus identifier stored in the genes table.
Old locus tagROSINTL182_06732Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG692720.1Sequence record reported by the local genomic context database.
Genomic interval72 645-74 162 nt1 518 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span72 645-74 961 ntGCF_000156535::NZ_GG692720.1::G00052
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000156535::NZ_GG692720.1::G00052Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG692720.1All displayed genes belong to this local TCS context.
Neighborhood span72 645-74 961 nt2 317 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
72 645 nt74 961 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
ROSINTL182_RS07720GCF_000156535#ROSINTL182_RS07720
HKClassicCurrent focus
72 645-74 162 nt · Forward (+)
ROSINTL182_RS07725GCF_000156535#ROSINTL182_RS07725
RRunclassified
74 134-74 961 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000156535#ROSINTL182_RS07720The current gene is the representative for this cluster.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1449218
Simplified PFAM architecture for HKOC_1449218
PFAM domain coverage: 224 / 505 aa (44.4%)
1 aa505 aa
HAMPHis_kinaseHATPase_c
- Simplified architecture: HAMP + His_kinase + HATPase_c
- Raw architecture: HAMP[210-253] | His_kinase[292-370] | HATPase_c[390-490]
- Domain count: 3
- Matched identifier: HKOC_1449218
- Positioned domains: HAMP 210-253 ; His_kinase 292-370 ; HATPase_c 390-490
Cluster members and taxonomy
Representative gene: GCF_000156535#ROSINTL182_RS07720
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 536 231 · GCF_000156535
AssemblyASM15653v1 · Scaffoldhaploid
Genome composition4 411 375 bp · 42,5% GCRoseburia intestinalis L1-82
Signal transduction countsGenes 112 · HK 51 · RR 58CheA 1 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusRoseburia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Roseburia
Related genes
Preview from the same derived genome key