1 HisKA#1
220-286 aa · 67 aa · 15.0% of protein
Raw token
HisKA:220:0.0000000000272:286:67:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF9524_RS00285
Histidine kinase, Classic
Enterococcus faecium TX0133a01 · GCF_000148325
ClassHKTypeClassicLength446 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000148325#HMPREF9524_RS00285Stable P2CS identifier used across views.
GenomeGCF_000148325Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length446 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage179 / 446 aa (40.1%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Domain-by-domain annotation2 items
2 HATPase_c#2
333-444 aa · 112 aa · 25.1% of protein
Raw token
HATPase_c:333:8e-27:444:113:109- Raw architecture: HisKA:220:0.0000000000272:286:67:64#HATPase_c:333:8e-27:444:113:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000148325::NZ_GL476016.1::G00002
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span11346-13365Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9524_00067RefSeq proteinWP_002286064.1
Context group ID
GCF_000148325::NZ_GL476016.1::G00002Context members
HMPREF9524_RS00285HMPREF9524_RS00290
Partner locus tags
HMPREF9524_RS00285HMPREF9524_RS00290
Partner old locus tags
HMPREF9524_00067HMPREF9524_00068
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_002286064.1Primary protein accession used for annex mappings.
UniProt accessionQ3Y3C5Primary UniProt accession resolved in the annex database.
UniProt IDQ3Y3C5_ENTFDDisplay identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
Reference hubs
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF9524_RS00285Primary locus identifier stored in the genes table.
Old locus tagHMPREF9524_00067Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GL476016.1Sequence record reported by the local genomic context database.
Genomic interval11 346-12 686 nt1 341 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span11 346-13 365 ntGCF_000148325::NZ_GL476016.1::G00002
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000148325::NZ_GL476016.1::G00002Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GL476016.1All displayed genes belong to this local TCS context.
Neighborhood span11 346-13 365 nt2 020 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
11 346 nt13 365 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HMPREF9524_RS00285GCF_000148325#HMPREF9524_RS00285
HKClassicCurrent focus
11 346-12 686 nt · Reverse (-)
HMPREF9524_RS00290GCF_000148325#HMPREF9524_RS00290
RROmpR
12 691-13 365 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000147315#HMPREF9527_RS11965Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2010498
Simplified PFAM architecture for HKOC_2010498
PFAM domain coverage: 177 / 446 aa (39.7%)
1 aa446 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[221-286] | HATPase_c[333-443]
- Domain count: 2
- Matched identifier: HKOC_2010498
- Positioned domains: HisKA 221-286 ; HATPase_c 333-443
Cluster members and taxonomy
Representative gene: GCF_000147315#HMPREF9527_RS11965
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 749 522 · GCF_000148325
AssemblyASM14832v1 · Scaffoldhaploid
Genome composition3 073 581 bp · 37,5% GCEnterococcus faecium TX0133a01
Signal transduction countsGenes 39 · HK 18 · RR 21CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus
Related genes
Preview from the same derived genome key