Gene detail

HMPREF9524_RS00035

Histidine kinase, Classic

Enterococcus faecium TX0133a01 · GCF_000148325

ClassHKTypeClassicLength298 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000148325#HMPREF9524_RS00035Stable P2CS identifier used across views.
GenomeGCF_000148325Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Selected clusterHKOC_2888633Run 6 · 5 sequences · id 100% · cov 80%
External referencesWP_002321567.1 · MIST4 HMPREF9524_RS00035RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length298 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage165 / 298 aa (55.4%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for HMPREF9524_RS00035
Domain-by-domain annotation2 items
1 HisKA#1
87-144 aa · 58 aa · 19.5% of protein
Raw tokenHisKA:87:0.0000000000000384:144:58:64
2 HATPase_c#2
191-297 aa · 107 aa · 35.9% of protein
Raw tokenHATPase_c:191:0.00000000000000272:297:114:109
  • Raw architecture: HisKA:87:0.0000000000000384:144:58:64#HATPase_c:191:0.00000000000000272:297:114:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000148325::NZ_GL476015.1::G00001
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span3762-5331Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9524_00007RefSeq proteinWP_002321567.1
Context group IDGCF_000148325::NZ_GL476015.1::G00001
Context members
HMPREF9524_RS00030HMPREF9524_RS00035
Partner locus tags
HMPREF9524_RS00030HMPREF9524_RS00035
Partner old locus tags
HMPREF9524_00006HMPREF9524_00007
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_002321567.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF9524_RS00035Primary locus identifier stored in the genes table.
Old locus tagHMPREF9524_00007Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GL476015.1Sequence record reported by the local genomic context database.
Genomic interval4 435-5 331 nt897 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span3 762-5 331 ntGCF_000148325::NZ_GL476015.1::G00001

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000148325::NZ_GL476015.1::G00001

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GL476015.1All displayed genes belong to this local TCS context.
Neighborhood span3 762-5 331 nt1 570 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
3 762 nt5 331 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HMPREF9524_RS00030GCF_000148325#HMPREF9524_RS00030
RROmpR

3 762-4 442 nt · Forward (+)

Old locus HMPREF9524_00006RefSeq WP_002287499.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2888633Run 6 · HK · 5 sequences
Representative sequenceGCF_000147235#HMPREF9525_RS12370Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2888633

Simplified PFAM architecture for HKOC_2888633

PFAM domain coverage: 157 / 298 aa (52.7%)

1 aa298 aa
HisKA: 87-144 aaHisKAHATPase_c: 192-290 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[87-144] | HATPase_c[192-290]
  • Domain count: 2
  • Matched identifier: HKOC_2888633
  • Positioned domains: HisKA 87-144 ; HATPase_c 192-290
Cluster members and taxonomy
Visualization

Representative gene: GCF_000147235#HMPREF9525_RS12370

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 749 522 · GCF_000148325
AssemblyASM14832v1 · Scaffoldhaploid
Genome composition3 073 581 bp · 37,5% GCEnterococcus faecium TX0133a01
Signal transduction countsGenes 39 · HK 18 · RR 21CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus

Related genes

Preview from the same derived genome key