Gene detail

HMPREF9495_RS06130

Histidine kinase, Classic

Enterococcus faecalis TX2141 · GCF_000148165

ClassHKTypeClassicLength489 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000148165#HMPREF9495_RS06130Stable P2CS identifier used across views.
GenomeGCF_000148165Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Selected clusterHKOC_1541232Run 6 · 478 sequences · id 100% · cov 80% · representative
External referencesWP_002366540.1 · R3KLS7 · MIST4 HMPREF9495_RS06130RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length489 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage243 / 489 aa (49.7%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for HMPREF9495_RS06130
Domain-by-domain annotation3 items
1 HAMP#1
186-251 aa · 66 aa · 13.5% of protein
Raw tokenHAMP:186:0.00000000000000557:251:66:69
2 HisKA#2
262-328 aa · 67 aa · 13.7% of protein
Raw tokenHisKA:262:0.00000000000000395:328:67:64
3 HATPase_c#3
373-482 aa · 110 aa · 22.5% of protein
Raw tokenHATPase_c:373:2.07e-31:482:110:109
  • Raw architecture: HAMP:186:0.00000000000000557:251:66:69#HisKA:262:0.00000000000000395:328:67:64#HATPase_c:373:2.07e-31:482:110:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000148165::NZ_GL457011.1::G00005
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span78157-80345Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9495_00524RefSeq proteinWP_002366540.1
Context group IDGCF_000148165::NZ_GL457011.1::G00005
Context members
HMPREF9495_RS06125HMPREF9495_RS06130
Partner locus tags
HMPREF9495_RS06125HMPREF9495_RS06130
Partner old locus tags
HMPREF9495_00523HMPREF9495_00524
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_002366540.1Primary protein accession used for annex mappings.
UniProt accessionR3KLS7Primary UniProt accession resolved in the annex database.
UniProt IDR3KLS7_ENTFLDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF9495_RS06130Primary locus identifier stored in the genes table.
Old locus tagHMPREF9495_00524Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GL457011.1Sequence record reported by the local genomic context database.
Genomic interval78 876-80 345 nt1 470 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span78 157-80 345 ntGCF_000148165::NZ_GL457011.1::G00005

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000148165::NZ_GL457011.1::G00005

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GL457011.1All displayed genes belong to this local TCS context.
Neighborhood span78 157-80 345 nt2 189 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
78 157 nt80 345 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HMPREF9495_RS06125GCF_000148165#HMPREF9495_RS06125
RROmpR

78 157-78 876 nt · Forward (+)

Old locus HMPREF9495_00523RefSeq WP_002381953.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1541232Run 6 · HK · 478 sequences
Representative sequenceGCF_000148165#HMPREF9495_RS06130The current gene is the representative for this cluster.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1541232

Simplified PFAM architecture for HKOC_1541232

PFAM domain coverage: 227 / 489 aa (46.4%)

1 aa489 aa
HAMP: 200-251 aaHAMPHisKA: 263-327 aaHisKAHATPase_c: 374-483 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[200-251] | HisKA[263-327] | HATPase_c[374-483]
  • Domain count: 3
  • Matched identifier: HKOC_1541232
  • Positioned domains: HAMP 200-251 ; HisKA 263-327 ; HATPase_c 374-483
Cluster members and taxonomy
Visualization

Representative gene: GCF_000148165#HMPREF9495_RS06130

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 749 492 · GCF_000148165
AssemblyASM14816v1 · Scaffoldhaploid
Genome composition2 903 110 bp · 37,5% GCEnterococcus faecalis TX2141
Signal transduction countsGenes 30 · HK 14 · RR 16CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus

Related genes

Preview from the same derived genome key