Gene detail

HMPREF9492_RS08220

Histidine kinase, Classic

Enterococcus faecalis DAPTO 512 · GCF_000148005

ClassHKTypeClassicLength589 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000148005#HMPREF9492_RS08220Stable P2CS identifier used across views.
GenomeGCF_000148005Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Selected clusterHKOC_1114760Run 6 · 832 sequences · id 100% · cov 80%
External referencesWP_002358984.1 · MIST4 HMPREF9492_RS08220RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

GAFHis_kinaseHATPase_c
Protein length589 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage304 / 589 aa (51.6%)Merged over positioned domains only.
Domain description1 GAF,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for HMPREF9492_RS08220
Domain-by-domain annotation3 items
1 GAF#1
244-363 aa · 120 aa · 20.4% of protein
Raw tokenGAF:244:0.00000145:363:128:133
2 His_kinase#2
378-456 aa · 79 aa · 13.4% of protein
Raw tokenHis_kinase:378:3.26e-30:456:80:80
3 HATPase_c#3
476-580 aa · 105 aa · 17.8% of protein
Raw tokenHATPase_c:476:0.0000000000011:580:109:109
  • Raw architecture: GAF:244:0.00000145:363:128:133#His_kinase:378:3.26e-30:456:80:80#HATPase_c:476:0.0000000000011:580:109:109
  • Domain description: 1 GAF,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000148005::NZ_GL455807.1::G00005
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span80481-82959Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9492_00941RefSeq proteinWP_002358984.1
Context group IDGCF_000148005::NZ_GL455807.1::G00005
Context members
HMPREF9492_RS08220HMPREF9492_RS08225
Partner locus tags
HMPREF9492_RS08220HMPREF9492_RS08225
Partner old locus tags
HMPREF9492_00941HMPREF9492_00942
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_002358984.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF9492_RS08220Primary locus identifier stored in the genes table.
Old locus tagHMPREF9492_00941Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GL455807.1Sequence record reported by the local genomic context database.
Genomic interval80 481-82 250 nt1 770 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span80 481-82 959 ntGCF_000148005::NZ_GL455807.1::G00005

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000148005::NZ_GL455807.1::G00005

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GL455807.1All displayed genes belong to this local TCS context.
Neighborhood span80 481-82 959 nt2 479 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
80 481 nt82 959 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HMPREF9492_RS08225GCF_000148005#HMPREF9492_RS08225
RRLytTR

82 231-82 959 nt · Forward (+)

Old locus HMPREF9492_00942RefSeq WP_002354828.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1114760Run 6 · HK · 832 sequences
Representative sequenceGCF_000147295#HMPREF9497_RS15605Use this link to inspect the representative gene detail.
PFAM architecture5TM-5TMR_LYT + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1114760

Simplified PFAM architecture for HKOC_1114760

PFAM domain coverage: 364 / 589 aa (61.8%)

1 aa589 aa
5TM-5TMR_LYT: 26-206 aa5TM-5TMR_LYTHis_kinase: 378-456 aaHis_kinaseHATPase_c: 476-579 aaHATPase_c
5TM-5TMR_LYTHis_kinaseHATPase_c
  • Simplified architecture: 5TM-5TMR_LYT + His_kinase + HATPase_c
  • Raw architecture: 5TM-5TMR_LYT[26-206] | His_kinase[378-456] | HATPase_c[476-579]
  • Domain count: 3
  • Matched identifier: HKOC_1114760
  • Positioned domains: 5TM-5TMR_LYT 26-206 ; His_kinase 378-456 ; HATPase_c 476-579
Cluster members and taxonomy
Visualization

Representative gene: GCF_000147295#HMPREF9497_RS15605

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 749 489 · GCF_000148005
AssemblyASM14800v1 · Scaffoldhaploid
Genome composition3 054 417 bp · 37,5% GCEnterococcus faecalis DAPTO 512
Signal transduction countsGenes 31 · HK 14 · RR 17CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus

Related genes

Preview from the same derived genome key