Gene detail

HMPREF9498_RS12515

Histidine kinase, Classic

Enterococcus faecalis TX4248 · GCF_000147925

ClassHKTypeClassicLength502 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000147925#HMPREF9498_RS12515Stable P2CS identifier used across views.
GenomeGCF_000147925Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Selected clusterHKOC_1454241Run 6 · 3194 sequences · id 100% · cov 80%
External referencesWP_002363430.1 · A0ABC9TPB6 · MIST4 HMPREF9498_RS12515RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length502 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage249 / 502 aa (49.6%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa502 aa
HAMP: 195-266 aa (72 aa)1HisKA: 270-336 aa (67 aa)2HATPase_c: 384-493 aa (110 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
195-266 aa · 72 aa · 14.3% of protein
Raw tokenHAMP:195:0.00000000000753:266:72:69
2 HisKA#2
270-336 aa · 67 aa · 13.3% of protein
Raw tokenHisKA:270:0.00000000000000867:336:67:64
3 HATPase_c#3
384-493 aa · 110 aa · 21.9% of protein
Raw tokenHATPase_c:384:1.17e-29:493:110:109
  • Raw architecture: HAMP:195:0.00000000000753:266:72:69#HisKA:270:0.00000000000000867:336:67:64#HATPase_c:384:1.17e-29:493:110:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000147925::NZ_GL454458.1::G00012
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span36369-38574Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9498_01805RefSeq proteinWP_002363430.1
Context group IDGCF_000147925::NZ_GL454458.1::G00012
Context members
HMPREF9498_RS12510HMPREF9498_RS12515
Partner locus tags
HMPREF9498_RS12510HMPREF9498_RS12515
Partner old locus tags
HMPREF9498_01804HMPREF9498_01805
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_002363430.1Primary protein accession used for annex mappings.
UniProt accessionA0ABC9TPB6Primary UniProt accession resolved in the annex database.
UniProt IDA0ABC9TPB6_ENTFLDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF9498_RS12515Primary locus identifier stored in the genes table.
Old locus tagHMPREF9498_01805Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GL454458.1Sequence record reported by the local genomic context database.
Genomic interval37 066-38 574 nt1 509 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span36 369-38 574 ntGCF_000147925::NZ_GL454458.1::G00012

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000147925::NZ_GL454458.1::G00012

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GL454458.1All displayed genes belong to this local TCS context.
Neighborhood span36 369-38 574 nt2 206 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
36 369 nt38 574 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HMPREF9498_RS12510GCF_000147925#HMPREF9498_RS12510
RROmpR

36 369-37 055 nt · Forward (+)

Old locus HMPREF9498_01804RefSeq WP_002355954.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1454241Run 6 · HK · 3194 sequences
Representative sequenceGCF_000390525#Q95_RS13535Use this link to inspect the representative gene detail.
PFAM architectureArlS_N + HAMP + HisKA + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1454241

Simplified PFAM architecture for HKOC_1454241

PFAM domain coverage: 372 / 504 aa (73.8%)

1 aa504 aa
ArlS_N: 45-189 aaArlS_NHAMP: 213-265 aaHAMPHisKA: 271-336 aaHisKAHATPase_c: 385-492 aaHATPase_c
ArlS_NHAMPHisKAHATPase_c
  • Simplified architecture: ArlS_N + HAMP + HisKA + HATPase_c
  • Raw architecture: ArlS_N[45-189] | HAMP[213-265] | HisKA[271-336] | HATPase_c[385-492]
  • Domain count: 4
  • Matched identifier: HKOC_1454241
  • Positioned domains: ArlS_N 45-189 ; HAMP 213-265 ; HisKA 271-336 ; HATPase_c 385-492
Cluster members and taxonomy
Visualization

Representative gene: GCF_000390525#Q95_RS13535

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 749 495 · GCF_000147925
AssemblyASM14792v1 · Scaffoldhaploid
Genome composition3 187 019 bp · 37,0% GCEnterococcus faecalis TX4248
Signal transduction countsGenes 31 · HK 14 · RR 17CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus

Related genes

Preview from the same derived genome key