Gene detail

HMPREF9498_RS07845

Histidine kinase, Classic

Enterococcus faecalis TX4248 · GCF_000147925

ClassHKTypeClassicLength609 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000147925#HMPREF9498_RS07845Stable P2CS identifier used across views.
GenomeGCF_000147925Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Selected clusterHKOC_1008573Run 6 · 8 sequences · id 100% · cov 80% · representative
External referencesWP_002402047.1 · A0A125W7P3 · MIST4 HMPREF9498_RS07845RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPPASHisKAHATPase_c
Protein length609 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage358 / 609 aa (58.8%)Merged over positioned domains only.
Domain description1 HAMP,1 PAS,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa609 aa
HAMP: 180-249 aa (70 aa)1PAS: 259-366 aa (108 aa)2HisKA: 375-442 aa (68 aa)3HATPase_c: 491-602 aa (112 aa)4
Domain-by-domain annotation4 items
1 HAMP#1
180-249 aa · 70 aa · 11.5% of protein
Raw tokenHAMP:180:1.1e-18:249:70:69
2 PAS#2
259-366 aa · 108 aa · 17.7% of protein
Raw tokenPAS:259:0.000000000107:366:115:113
3 HisKA#3
375-442 aa · 68 aa · 11.2% of protein
Raw tokenHisKA:375:4.63e-19:442:68:64
4 HATPase_c#4
491-602 aa · 112 aa · 18.4% of protein
Raw tokenHATPase_c:491:5.04e-33:602:112:109
  • Raw architecture: HAMP:180:1.1e-18:249:70:69#PAS:259:0.000000000107:366:115:113#HisKA:375:4.63e-19:442:68:64#HATPase_c:491:5.04e-33:602:112:109
  • Domain description: 1 HAMP,1 PAS,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000147925::NZ_GL454430.1::G00006
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span61871-64411Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9498_00826RefSeq proteinWP_002402047.1
Context group IDGCF_000147925::NZ_GL454430.1::G00006
Context members
HMPREF9498_RS07845HMPREF9498_RS07850
Partner locus tags
HMPREF9498_RS07845HMPREF9498_RS07850
Partner old locus tags
HMPREF9498_00826HMPREF9498_00827
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_002402047.1Primary protein accession used for annex mappings.
UniProt accessionA0A125W7P3Primary UniProt accession resolved in the annex database.
UniProt IDA0A125W7P3_ENTFLDisplay identifier provided by UniProt.
GO / PubMed5 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF9498_RS07845Primary locus identifier stored in the genes table.
Old locus tagHMPREF9498_00826Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GL454430.1Sequence record reported by the local genomic context database.
Genomic interval61 871-63 700 nt1 830 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span61 871-64 411 ntGCF_000147925::NZ_GL454430.1::G00006

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000147925::NZ_GL454430.1::G00006

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GL454430.1All displayed genes belong to this local TCS context.
Neighborhood span61 871-64 411 nt2 541 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
61 871 nt64 411 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HMPREF9498_RS07850GCF_000147925#HMPREF9498_RS07850
RROmpR

63 707-64 411 nt · Reverse (-)

Old locus HMPREF9498_00827RefSeq WP_002357947.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1008573Run 6 · HK · 8 sequences
Representative sequenceGCF_000147925#HMPREF9498_RS07845The current gene is the representative for this cluster.
PFAM architectureCache_WalK + HAMP + PAS + HisKA + HATPase_c5 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1008573

Simplified PFAM architecture for HKOC_1008573

PFAM domain coverage: 424 / 609 aa (69.6%)

1 aa609 aa
Cache_WalK: 79-164 aaCache_WalKHAMP: 197-249 aaHAMPPAS: 260-366 aaPASHisKA: 376-442 aaHisKAHATPase_c: 491-601 aaHATPase_c
Cache_WalKHAMPPASHisKAHATPase_c
  • Simplified architecture: Cache_WalK + HAMP + PAS + HisKA + HATPase_c
  • Raw architecture: Cache_WalK[79-164] | HAMP[197-249] | PAS[260-366] | HisKA[376-442] | HATPase_c[491-601]
  • Domain count: 5
  • Matched identifier: HKOC_1008573
  • Positioned domains: Cache_WalK 79-164 ; HAMP 197-249 ; PAS 260-366 ; HisKA 376-442 ; HATPase_c 491-601
Cluster members and taxonomy
Visualization

Representative gene: GCF_000147925#HMPREF9498_RS07845

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 749 495 · GCF_000147925
AssemblyASM14792v1 · Scaffoldhaploid
Genome composition3 187 019 bp · 37,0% GCEnterococcus faecalis TX4248
Signal transduction countsGenes 31 · HK 14 · RR 17CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus

Related genes

Preview from the same derived genome key