Gene detail

HMPREF9500_RS06815

Histidine kinase, Classic

Enterococcus faecalis TX0017 · GCF_000147905

ClassHKTypeClassicLength576 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000147905#HMPREF9500_RS06815Stable P2CS identifier used across views.
GenomeGCF_000147905Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Selected clusterHKOC_1182884Run 6 · 1349 sequences · id 100% · cov 80%
External referencesWP_002356857.1 · A0ABC9TIV0 · MIST4 HMPREF9500_RS06815RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHis_kinaseHATPase_c
Protein length576 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage263 / 576 aa (45.7%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa576 aa
HAMP: 288-360 aa (73 aa)1His_kinase: 375-453 aa (79 aa)2HATPase_c: 464-574 aa (111 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
288-360 aa · 73 aa · 12.7% of protein
Raw tokenHAMP:288:0.0000000855:360:73:69
2 His_kinase#2
375-453 aa · 79 aa · 13.7% of protein
Raw tokenHis_kinase:375:8.39e-28:453:80:80
3 HATPase_c#3
464-574 aa · 111 aa · 19.3% of protein
Raw tokenHATPase_c:464:0.0000000000136:574:113:109
  • Raw architecture: HAMP:288:0.0000000855:360:73:69#His_kinase:375:8.39e-28:453:80:80#HATPase_c:464:0.0000000000136:574:113:109
  • Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000147905::NZ_GL454158.1::G00005
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span5472-8695Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9500_00654RefSeq proteinWP_002356857.1
Context group IDGCF_000147905::NZ_GL454158.1::G00005
Context members
HMPREF9500_RS06815HMPREF9500_RS06820
Partner locus tags
HMPREF9500_RS06815HMPREF9500_RS06820
Partner old locus tags
HMPREF9500_00654HMPREF9500_00655
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_002356857.1Primary protein accession used for annex mappings.
UniProt accessionA0ABC9TIV0Primary UniProt accession resolved in the annex database.
UniProt IDA0ABC9TIV0_ENTFLDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF9500_RS06815Primary locus identifier stored in the genes table.
Old locus tagHMPREF9500_00654Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GL454158.1Sequence record reported by the local genomic context database.
Genomic interval5 472-7 202 nt1 731 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span5 472-8 695 ntGCF_000147905::NZ_GL454158.1::G00005

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000147905::NZ_GL454158.1::G00005

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GL454158.1All displayed genes belong to this local TCS context.
Neighborhood span5 472-8 695 nt3 224 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
5 472 nt8 695 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HMPREF9500_RS06820GCF_000147905#HMPREF9500_RS06820
RRunclassified

7 214-8 695 nt · Forward (+)

Old locus HMPREF9500_00655RefSeq WP_002366967.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1182884Run 6 · HK · 1349 sequences
Representative sequenceGCF_000147215#HMPREF9504_RS15130Use this link to inspect the representative gene detail.
PFAM architectureHis_kinase + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1182884

Simplified PFAM architecture for HKOC_1182884

PFAM domain coverage: 180 / 576 aa (31.3%)

1 aa576 aa
His_kinase: 375-453 aaHis_kinaseHATPase_c: 474-574 aaHATPase_c
His_kinaseHATPase_c
  • Simplified architecture: His_kinase + HATPase_c
  • Raw architecture: His_kinase[375-453] | HATPase_c[474-574]
  • Domain count: 2
  • Matched identifier: HKOC_1182884
  • Positioned domains: His_kinase 375-453 ; HATPase_c 474-574
Cluster members and taxonomy
Visualization

Representative gene: GCF_000147215#HMPREF9504_RS15130

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 749 497 · GCF_000147905
AssemblyASM14790v1 · Scaffoldhaploid
Genome composition2 997 067 bp · 37,5% GCEnterococcus faecalis TX0017
Signal transduction countsGenes 28 · HK 13 · RR 15CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus

Related genes

Preview from the same derived genome key