Gene detail

HMPREF9503_RS05490

Histidine kinase, Classic

Enterococcus faecalis TX0043 · GCF_000147515

ClassHKTypeClassicLength447 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000147515#HMPREF9503_RS05490Stable P2CS identifier used across views.
GenomeGCF_000147515Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Selected clusterHKOC_1999519Run 6 · 400 sequences · id 100% · cov 80%
External referencesWP_002393835.1 · MIST4 HMPREF9503_RS05490RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length447 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage258 / 447 aa (57.7%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa447 aa
HAMP: 130-208 aa (79 aa)1HisKA: 220-284 aa (65 aa)2HATPase_c: 329-442 aa (114 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
130-208 aa · 79 aa · 17.7% of protein
Raw tokenHAMP:130:0.000000222:208:79:69
2 HisKA#2
220-284 aa · 65 aa · 14.5% of protein
Raw tokenHisKA:220:0.00000000000000934:284:65:64
3 HATPase_c#3
329-442 aa · 114 aa · 25.5% of protein
Raw tokenHATPase_c:329:7.99e-33:442:114:109
  • Raw architecture: HAMP:130:0.000000222:208:79:69#HisKA:220:0.00000000000000934:284:65:64#HATPase_c:329:7.99e-33:442:114:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_000147515::NZ_GL454499.1::G00004
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span25523-26866Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9503_00457RefSeq proteinWP_002393835.1
Context group IDGCF_000147515::NZ_GL454499.1::G00004
Context members
HMPREF9503_RS05490
Partner locus tags
HMPREF9503_RS05490
Partner old locus tags
HMPREF9503_00457
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_002393835.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF9503_RS05490Primary locus identifier stored in the genes table.
Old locus tagHMPREF9503_00457Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GL454499.1Sequence record reported by the local genomic context database.
Genomic interval25 523-26 866 nt1 344 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span25 523-26 866 ntGCF_000147515::NZ_GL454499.1::G00004

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000147515::NZ_GL454499.1::G00004

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GL454499.1All displayed genes belong to this local TCS context.
Neighborhood span25 523-26 866 nt1 344 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
25 523 nt26 866 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1999519Run 6 · HK · 400 sequences
Representative sequenceGCF_000147215#HMPREF9504_RS08675Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1999519

Simplified PFAM architecture for HKOC_1999519

PFAM domain coverage: 178 / 447 aa (39.8%)

1 aa447 aa
HisKA: 220-284 aaHisKAHATPase_c: 330-442 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[220-284] | HATPase_c[330-442]
  • Domain count: 2
  • Matched identifier: HKOC_1999519
  • Positioned domains: HisKA 220-284 ; HATPase_c 330-442
Cluster members and taxonomy
Visualization

Representative gene: GCF_000147215#HMPREF9504_RS08675

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 749 500 · GCF_000147515
AssemblyASM14751v1 · Scaffoldhaploid
Genome composition2 812 052 bp · 37,5% GCEnterococcus faecalis TX0043
Signal transduction countsGenes 25 · HK 12 · RR 13CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus

Related genes

Preview from the same derived genome key