1 HisKA_3#1
172-235 aa · 64 aa · 17.8% of protein
Raw token
HisKA_3:172:5.94e-16:235:66:68P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF9527_RS03340
Histidine kinase, Classic
Enterococcus faecium TX0133C · GCF_000147315
ClassHKTypeClassicLength359 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000147315#HMPREF9527_RS03340Stable P2CS identifier used across views.
GenomeGCF_000147315Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Domain signature
Compact overview inferred from the domain field
HisKA_3HATPase_c
Protein length359 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage146 / 359 aa (40.7%)Merged over positioned domains only.
Domain description1 HisKA_3,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa359 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
275-356 aa · 82 aa · 22.8% of protein
Raw token
HATPase_c:275:0.000000242:356:100:109- Raw architecture: HisKA_3:172:5.94e-16:235:66:68#HATPase_c:275:0.000000242:356:100:109
- Domain description: 1 HisKA_3,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000147315::NZ_GL455159.1::G00005
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span11454-13189Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9527_00728RefSeq proteinWP_002317394.1
Context group ID
GCF_000147315::NZ_GL455159.1::G00005Context members
HMPREF9527_RS03335HMPREF9527_RS03340
Partner locus tags
HMPREF9527_RS03335HMPREF9527_RS03340
Partner old locus tags
HMPREF9527_00727HMPREF9527_00728
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_002317394.1Primary protein accession used for annex mappings.
UniProt accessionA0AAV3GYF7Primary UniProt accession resolved in the annex database.
UniProt IDA0AAV3GYF7_ENTFCDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.
Reference hubs
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF9527_RS03340Primary locus identifier stored in the genes table.
Old locus tagHMPREF9527_00728Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GL455159.1Sequence record reported by the local genomic context database.
Genomic interval12 080-13 189 nt1 110 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span11 454-13 189 ntGCF_000147315::NZ_GL455159.1::G00005
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000147315::NZ_GL455159.1::G00005Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GL455159.1All displayed genes belong to this local TCS context.
Neighborhood span11 454-13 189 nt1 736 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
11 454 nt13 189 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HMPREF9527_RS03335GCF_000147315#HMPREF9527_RS03335
RRNarL
11 454-12 083 nt · Reverse (-)
HMPREF9527_RS03340GCF_000147315#HMPREF9527_RS03340
HKClassicCurrent focus
12 080-13 189 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000172675#EFME1162_RS10350Use this link to inspect the representative gene detail.
PFAM architectureHisKA_3 + HATPase_c_52 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2691252
Simplified PFAM architecture for HKOC_2691252
PFAM domain coverage: 150 / 369 aa (40.7%)
1 aa369 aa
HisKA_3HATPase_c_5
- Simplified architecture: HisKA_3 + HATPase_c_5
- Raw architecture: HisKA_3[182-245] | HATPase_c_5[279-364]
- Domain count: 2
- Matched identifier: HKOC_2691252
- Positioned domains: HisKA_3 182-245 ; HATPase_c_5 279-364
Cluster members and taxonomy
Representative gene: GCF_000172675#EFME1162_RS10350
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 749 525 · GCF_000147315
AssemblyASM14731v1 · Scaffoldhaploid
Genome composition2 907 861 bp · 37,5% GCEnterococcus faecium TX0133C
Signal transduction countsGenes 36 · HK 17 · RR 19CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus
Related genes
Preview from the same derived genome key