1 Response_reg#1
7-112 aa · 106 aa · 23.0% of protein
Raw token
Response_reg:7:2.06e-35:112:106:111P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
ECUMN_RS13770
Response regulator, unclassified
Escherichia coli UMN026 · GCF_000026325
ClassRRTypePrrALength461 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000026325#ECUMN_RS13770Stable P2CS identifier used across views.
GenomeGCF_000026325Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Domain signature
Compact overview inferred from the domain field
Response_regAAAHTH_8
Protein length461 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage295 / 461 aa (64.0%)Merged over positioned domains only.
Domain description1 Response_reg,1 AAA,1 HTH_8Summary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa461 aa
Domain-by-domain annotation3 items
2 AAA#2
169-319 aa · 151 aa · 32.8% of protein
Raw token
AAA:169:0.00000000281:319:165:1303 HTH_8#3
417-454 aa · 38 aa · 8.2% of protein
Raw token
HTH_8:417:0.000000000000188:454:38:40- Raw architecture: Response_reg:7:2.06e-35:112:106:111#AAA:169:0.00000000281:319:165:130#HTH_8:417:0.000000000000188:454:38:40
- Domain description: 1 Response_reg,1 AAA,1 HTH_8
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000026325::NC_011751.1::G00020
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2620515-2623723Genomic interval covered by the local TCS group.
Identifiers
Old locus tagECUMN_2558RefSeq proteinWP_000125283.1
Context group ID
GCF_000026325::NC_011751.1::G00020Context members
ECUMN_RS13765ECUMN_RS13770
Partner locus tags
ECUMN_RS13765ECUMN_RS13770
Partner old locus tags
ECUMN_2557ECUMN_2558
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_000125283.1Primary protein accession used for annex mappings.
UniProt accessionB7N5I3Primary UniProt accession resolved in the annex database.
UniProt IDB7N5I3_ECOLUDisplay identifier provided by UniProt.
GO / PubMed5 / 1Unique GO terms and literature references available below.
Reference hubs
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagECUMN_RS13770Primary locus identifier stored in the genes table.
Old locus tagECUMN_2558Legacy locus tag recovered from the local context mapping.
Contig / repliconNC_011751.1Sequence record reported by the local genomic context database.
Genomic interval2 622 338-2 623 723 nt1 386 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span2 620 515-2 623 723 ntGCF_000026325::NC_011751.1::G00020
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000026325::NC_011751.1::G00020Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_011751.1All displayed genes belong to this local TCS context.
Neighborhood span2 620 515-2 623 723 nt3 209 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 620 515 nt2 623 723 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
ECUMN_RS13765GCF_000026325#ECUMN_RS13765
HKClassic
2 620 515-2 622 341 nt · Forward (+)
ECUMN_RS13770GCF_000026325#ECUMN_RS13770
RRPrrACurrent focus
2 622 338-2 623 723 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000026325#ECUMN_RS13770The current gene is the representative for this cluster.
PFAM architectureResponse_reg + Sigma54_activat + AAA_lid_14 + HTH_84 domains in the representative PFAM annotation.
PFAM architecture for RROC_0236084
Simplified PFAM architecture for RROC_0236084
PFAM domain coverage: 393 / 461 aa (85.2%)
1 aa461 aa
Response_regSigma54_activatAAA_lid_14HTH_8
- Simplified architecture: Response_reg + Sigma54_activat + AAA_lid_14 + HTH_8
- Raw architecture: Response_reg[7-115] | Sigma54_activat[145-311] | AAA_lid_14[317-393] | HTH_8[415-454]
- Domain count: 4
- Matched identifier: RROC_0236084
- Positioned domains: Response_reg 7-115 ; Response_reg 7-115 ; Sigma54_activat 145-311 ; Sigma54_activat 145-311 ; AAA_lid_14 317-393 ; AAA_lid_14 317-393 ; HTH_8 415-454 ; HTH_8 415-454
Cluster members and taxonomy
Representative gene: GCF_000026325#ECUMN_RS13770
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 585 056 · GCF_000026325
AssemblyASM2632v2 · Chromosomehaploid
Genome composition5 358 200 bp · 50,5% GCEscherichia coli UMN026
Signal transduction countsGenes 61 · HK 29 · RR 32CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia
Related genes
Preview from the same derived genome key