1 Response_reg#1
9-118 aa · 110 aa · 24.8% of protein
Raw token
Response_reg:9:2.88e-39:118:110:111P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
ECH74115_RS19020
Response regulator, unclassified
Escherichia coli O157:H7 str. EC4115 · GCF_000021125
ClassRRTypeunclassifiedLength444 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000021125#ECH74115_RS19020Stable P2CS identifier used across views.
GenomeGCF_000021125Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Domain signature
Compact overview inferred from the domain field
Response_regAAA_5
Protein length444 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage230 / 444 aa (51.8%)Merged over positioned domains only.
Domain description1 Response_reg,1 AAA_5Summary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa444 aa
Domain-by-domain annotation2 items
2 AAA_5#2
159-278 aa · 120 aa · 27.0% of protein
Raw token
AAA_5:159:0.0000348:278:128:135- Raw architecture: Response_reg:9:2.88e-39:118:110:111#AAA_5:159:0.0000348:278:128:135
- Domain description: 1 Response_reg,1 AAA_5
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelorphanGCF_000021125::NC_011353.1::G00025
Group size11 locus tag listed below.
HK / RR0 / 1Counts resolved for the local TCS neighborhood.
Context span3511952-3513286Genomic interval covered by the local TCS group.
Identifiers
Old locus tagECH74115_3788RefSeq proteinWP_001295369.1
Context group ID
GCF_000021125::NC_011353.1::G00025Context members
ECH74115_RS19020
Partner locus tags
ECH74115_RS19020
Partner old locus tags
ECH74115_3788
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_001295369.1Primary protein accession used for annex mappings.
UniProt accessionI6DWB8Primary UniProt accession resolved in the annex database.
UniProt IDI6DWB8_SHIBODisplay identifier provided by UniProt.
GO / PubMed5 / 0Unique GO terms and literature references available below.
Reference hubs
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagECH74115_RS19020Primary locus identifier stored in the genes table.
Old locus tagECH74115_3788Legacy locus tag recovered from the local context mapping.
Contig / repliconNC_011353.1Sequence record reported by the local genomic context database.
Genomic interval3 511 952-3 513 286 nt1 335 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span3 511 952-3 513 286 ntGCF_000021125::NC_011353.1::G00025
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000021125::NC_011353.1::G00025Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_011353.1All displayed genes belong to this local TCS context.
Neighborhood span3 511 952-3 513 286 nt1 335 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
3 511 952 nt3 513 286 nt
Neighborhood gene cards
1 gene in the current local neighborhood.
ECH74115_RS19020GCF_000021125#ECH74115_RS19020
RRunclassifiedCurrent focus
3 511 952-3 513 286 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
PFAM architectureResponse_reg + Sigma54_activat + AAA_lid_143 domains in the representative PFAM annotation.
PFAM architecture for RROC_0317217
Simplified PFAM architecture for RROC_0317217
PFAM domain coverage: 353 / 444 aa (79.5%)
1 aa444 aa
Response_regSigma54_activatAAA_lid_14
- Simplified architecture: Response_reg + Sigma54_activat + AAA_lid_14
- Raw architecture: Response_reg[9-117] | Sigma54_activat[136-302] | AAA_lid_14[309-385]
- Domain count: 3
- Matched identifier: RROC_0317217
- Positioned domains: Response_reg 9-117 ; Response_reg 9-117 ; Sigma54_activat 136-302 ; Sigma54_activat 136-302 ; AAA_lid_14 309-385 ; AAA_lid_14 309-385
Cluster members and taxonomy
Representative gene: GCF_000005845#b2554
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 444 450 · GCF_000021125
AssemblyASM2112v1 · Complete Genomehaploid
Genome composition5 704 171 bp · 50,5% GCEscherichia coli O157:H7 str. EC4115
Signal transduction countsGenes 64 · HK 31 · RR 33CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia
Related genes
Preview from the same derived genome key