1 HAMP#1
188-257 aa · 70 aa · 14.5% of protein
Raw token
HAMP:188:0.0000000000753:257:71:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
ECH74115_RS03665
Histidine kinase, Classic
Escherichia coli O157:H7 str. EC4115 · GCF_000021125
ClassHKTypeClassicLength482 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000021125#ECH74115_RS03665Stable P2CS identifier used across views.
GenomeGCF_000021125Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length482 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage248 / 482 aa (51.5%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa482 aa
Domain-by-domain annotation3 items
2 HisKA#2
261-327 aa · 67 aa · 13.9% of protein
Raw token
HisKA:261:0.0000000000012:327:67:643 HATPase_c#3
371-481 aa · 111 aa · 23.0% of protein
Raw token
HATPase_c:371:6.42e-29:481:112:109- Raw architecture: HAMP:188:0.0000000000753:257:71:69#HisKA:261:0.0000000000012:327:67:64#HATPase_c:371:6.42e-29:481:112:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000021125::NC_011353.1::G00004
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span679257-681378Genomic interval covered by the local TCS group.
Identifiers
Old locus tagECH74115_0650RefSeq proteinWP_000253799.1
Context group ID
GCF_000021125::NC_011353.1::G00004Context members
ECH74115_RS03665ECH74115_RS03670
Partner locus tags
ECH74115_RS03665ECH74115_RS03670
Partner old locus tags
ECH74115_0650ECH74115_0651
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_000253799.1Primary protein accession used for annex mappings.
UniProt accessionA0AAV3HDZ4Primary UniProt accession resolved in the annex database.
UniProt IDA0AAV3HDZ4_ECOLXDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagECH74115_RS03665Primary locus identifier stored in the genes table.
Old locus tagECH74115_0650Legacy locus tag recovered from the local context mapping.
Contig / repliconNC_011353.1Sequence record reported by the local genomic context database.
Genomic interval679 257-680 705 nt1 449 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span679 257-681 378 ntGCF_000021125::NC_011353.1::G00004
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000021125::NC_011353.1::G00004Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_011353.1All displayed genes belong to this local TCS context.
Neighborhood span679 257-681 378 nt2 122 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
679 257 nt681 378 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
ECH74115_RS03665GCF_000021125#ECH74115_RS03665
HKClassicCurrent focus
679 257-680 705 nt · Reverse (-)
ECH74115_RS03670GCF_000021125#ECH74115_RS03670
RROmpR
680 695-681 378 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000178315#EC4009_RS0114620Use this link to inspect the representative gene detail.
PFAM architectureCusS + HAMP + HisKA + HATPase_c4 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1584145
Simplified PFAM architecture for HKOC_1584145
PFAM domain coverage: 397 / 484 aa (82.0%)
1 aa484 aa
CusSHAMPHisKAHATPase_c
- Simplified architecture: CusS + HAMP + HisKA + HATPase_c
- Raw architecture: CusS[8-180] | HAMP[210-257] | HisKA[262-326] | HATPase_c[371-481]
- Domain count: 4
- Matched identifier: HKOC_1584145
- Positioned domains: CusS 8-180 ; HAMP 210-257 ; HisKA 262-326 ; HATPase_c 371-481
Cluster members and taxonomy
Representative gene: GCF_000178315#EC4009_RS0114620
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 444 450 · GCF_000021125
AssemblyASM2112v1 · Complete Genomehaploid
Genome composition5 704 171 bp · 50,5% GCEscherichia coli O157:H7 str. EC4115
Signal transduction countsGenes 64 · HK 31 · RR 33CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia
Related genes
Preview from the same derived genome key