Gene detail

EUBREC_RS04665

Histidine kinase, Classic

Agathobacter rectalis ATCC 33656 · GCF_000020605

ClassHKTypeClassicLength588 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000020605#EUBREC_RS04665Stable P2CS identifier used across views.
GenomeGCF_000020605Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Agathobacter
Selected clusterHKOC_1119939Run 6 · 2 sequences · id 100% · cov 80% · representative
External referencesWP_012741908.1 · C4ZGL0 · MIST4 EUBREC_RS04665RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHis_kinaseHATPase_c
Protein length588 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage258 / 588 aa (43.9%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa588 aa
HAMP: 289-358 aa (70 aa)1His_kinase: 380-459 aa (80 aa)2HATPase_c: 479-586 aa (108 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
289-358 aa · 70 aa · 11.9% of protein
Raw tokenHAMP:289:0.000000882:358:70:69
2 His_kinase#2
380-459 aa · 80 aa · 13.6% of protein
Raw tokenHis_kinase:380:2.78e-31:459:80:80
3 HATPase_c#3
479-586 aa · 108 aa · 18.4% of protein
Raw tokenHATPase_c:479:0.000000000331:586:108:109
  • Raw architecture: HAMP:289:0.000000882:358:70:69#His_kinase:380:2.78e-31:459:80:80#HATPase_c:479:0.000000000331:586:108:109
  • Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000020605::NC_012781.1::G00013
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span944239-947611Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEUBREC_1045RefSeq proteinWP_012741908.1
Context group IDGCF_000020605::NC_012781.1::G00013
Context members
EUBREC_RS04665EUBREC_RS04670
Partner locus tags
EUBREC_RS04665EUBREC_RS04670
Partner old locus tags
EUBREC_1045EUBREC_1046
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_012741908.1Primary protein accession used for annex mappings.
UniProt accessionC4ZGL0Primary UniProt accession resolved in the annex database.
UniProt IDC4ZGL0_AGARVDisplay identifier provided by UniProt.
GO / PubMed2 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagEUBREC_RS04665Primary locus identifier stored in the genes table.
Old locus tagEUBREC_1045Legacy locus tag recovered from the local context mapping.
Contig / repliconNC_012781.1Sequence record reported by the local genomic context database.
Genomic interval944 239-946 005 nt1 767 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span944 239-947 611 ntGCF_000020605::NC_012781.1::G00013

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000020605::NC_012781.1::G00013

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_012781.1All displayed genes belong to this local TCS context.
Neighborhood span944 239-947 611 nt3 373 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
944 239 nt947 611 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

EUBREC_RS04665GCF_000020605#EUBREC_RS04665
HKClassicCurrent focus

944 239-946 005 nt · Forward (+)

Old locus EUBREC_1045RefSeq WP_012741908.1
EUBREC_RS04670GCF_000020605#EUBREC_RS04670
RRunclassified

946 016-947 611 nt · Forward (+)

Old locus EUBREC_1046RefSeq WP_012741909.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1119939Run 6 · HK · 2 sequences
Representative sequenceGCF_000020605#EUBREC_RS04665The current gene is the representative for this cluster.
PFAM architectureHis_kinase + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1119939

Simplified PFAM architecture for HKOC_1119939

PFAM domain coverage: 187 / 588 aa (31.8%)

1 aa588 aa
His_kinase: 380-459 aaHis_kinaseHATPase_c: 479-585 aaHATPase_c
His_kinaseHATPase_c
  • Simplified architecture: His_kinase + HATPase_c
  • Raw architecture: His_kinase[380-459] | HATPase_c[479-585]
  • Domain count: 2
  • Matched identifier: HKOC_1119939
  • Positioned domains: His_kinase 380-459 ; HATPase_c 479-585
Cluster members and taxonomy
Visualization

Representative gene: GCF_000020605#EUBREC_RS04665

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 515 619 · GCF_000020605
AssemblyASM2060v1 · Complete Genomehaploid
Genome composition3 449 685 bp · 41,5% GCAgathobacter rectalis ATCC 33656
Signal transduction countsGenes 86 · HK 39 · RR 46CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusAgathobacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Agathobacter

Related genes

Preview from the same derived genome key