1 HisKA#1
237-299 aa · 63 aa · 13.8% of protein
Raw token
HisKA:237:0.0000000000012:299:63:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
SFV_RS22430
Histidine kinase, Classic
Shigella flexneri 5 str. 8401 · GCF_000013585
ClassHKTypeClassicLength458 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000013585#SFV_RS22430Stable P2CS identifier used across views.
GenomeGCF_000013585Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Shigella
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length458 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage170 / 458 aa (37.1%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa458 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
345-451 aa · 107 aa · 23.4% of protein
Raw token
HATPase_c:345:7.78e-34:451:110:109- Raw architecture: HisKA:237:0.0000000000012:299:63:64#HATPase_c:345:7.78e-34:451:110:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000013585::NC_008258.1::G00032
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span4192091-4194789Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSFV_4075RefSeq proteinWP_001211915.1
Context group ID
GCF_000013585::NC_008258.1::G00032Context members
SFV_RS22430SFV_RS22435
Partner locus tags
SFV_RS22430SFV_RS22435
Partner old locus tags
SFV_4075SFV_4076
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_001211915.1Primary protein accession used for annex mappings.
UniProt accessionA0A4P7TR34Primary UniProt accession resolved in the annex database.
UniProt IDA0A4P7TR34_SHIFMDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagSFV_RS22430Primary locus identifier stored in the genes table.
Old locus tagSFV_4075Legacy locus tag recovered from the local context mapping.
Contig / repliconNC_008258.1Sequence record reported by the local genomic context database.
Genomic interval4 192 091-4 193 467 nt1 377 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span4 192 091-4 194 789 ntGCF_000013585::NC_008258.1::G00032
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000013585::NC_008258.1::G00032Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_008258.1All displayed genes belong to this local TCS context.
Neighborhood span4 192 091-4 194 789 nt2 699 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
4 192 091 nt4 194 789 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
SFV_RS22430GCF_000013585#SFV_RS22430
HKClassicCurrent focus
4 192 091-4 193 467 nt · Forward (+)
SFV_RS22435GCF_000013585#SFV_RS22435
RRNtrC
4 193 464-4 194 789 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000013585#SFV_RS22430The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1858289
Simplified PFAM architecture for HKOC_1858289
PFAM domain coverage: 168 / 458 aa (36.7%)
1 aa458 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[238-300] | HATPase_c[346-450]
- Domain count: 2
- Matched identifier: HKOC_1858289
- Positioned domains: HisKA 238-300 ; HATPase_c 346-450
Cluster members and taxonomy
Representative gene: GCF_000013585#SFV_RS22430
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 373 384 · GCF_000013585
AssemblyASM1358v1 · Complete Genomehaploid
Genome composition4 574 284 bp · 51,0% GCShigella flexneri 5 str. 8401
Signal transduction countsGenes 55 · HK 25 · RR 30CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusShigella
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Shigella
Related genes
Preview from the same derived genome key