Gene detail

SFV_RS18770

Histidine kinase, Classic

Shigella flexneri 5 str. 8401 · GCF_000013585

ClassHKTypeClassicLength450 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000013585#SFV_RS18770Stable P2CS identifier used across views.
GenomeGCF_000013585Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Shigella
Selected clusterHKOC_1957158Run 6 · 25240 sequences · id 100% · cov 80%
External referencesWP_001253696.1 · A0A8E0KT74 · MIST4 SFV_RS18770RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length450 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage236 / 450 aa (52.4%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa450 aa
HAMP: 160-229 aa (70 aa)1HisKA: 234-293 aa (60 aa)2HATPase_c: 334-439 aa (106 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
160-229 aa · 70 aa · 15.6% of protein
Raw tokenHAMP:160:0.0000000000438:229:70:69
2 HisKA#2
234-293 aa · 60 aa · 13.3% of protein
Raw tokenHisKA:234:0.00000000000328:293:63:64
3 HATPase_c#3
334-439 aa · 106 aa · 23.6% of protein
Raw tokenHATPase_c:334:2.33e-27:439:109:109
  • Raw architecture: HAMP:160:0.0000000000438:229:70:69#HisKA:234:0.00000000000328:293:63:64#HATPase_c:334:2.33e-27:439:109:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000013585::NC_008258.1::G00028
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span3465717-3467785Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSFV_3409RefSeq proteinWP_001253696.1
Context group IDGCF_000013585::NC_008258.1::G00028
Context members
SFV_RS18770SFV_RS18775
Partner locus tags
SFV_RS18770SFV_RS18775
Partner old locus tags
SFV_3409SFV_3410
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_001253696.1Primary protein accession used for annex mappings.
UniProt accessionA0A8E0KT74Primary UniProt accession resolved in the annex database.
UniProt IDA0A8E0KT74_ECOLXDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagSFV_RS18770Primary locus identifier stored in the genes table.
Old locus tagSFV_3409Legacy locus tag recovered from the local context mapping.
Contig / repliconNC_008258.1Sequence record reported by the local genomic context database.
Genomic interval3 465 717-3 467 069 nt1 353 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span3 465 717-3 467 785 ntGCF_000013585::NC_008258.1::G00028

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000013585::NC_008258.1::G00028

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_008258.1All displayed genes belong to this local TCS context.
Neighborhood span3 465 717-3 467 785 nt2 069 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
3 465 717 nt3 467 785 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

SFV_RS18770GCF_000013585#SFV_RS18770
HKClassicCurrent focus

3 465 717-3 467 069 nt · Reverse (-)

Old locus SFV_3409RefSeq WP_001253696.1
SFV_RS18775GCF_000013585#SFV_RS18775
RROmpR

3 467 066-3 467 785 nt · Reverse (-)

Old locus SFV_3410RefSeq WP_001157751.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1957158Run 6 · HK · 25240 sequences
Representative sequenceGCF_030346725#QT350_RS08200Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1957158

Simplified PFAM architecture for HKOC_1957158

PFAM domain coverage: 213 / 451 aa (47.2%)

1 aa451 aa
HAMP: 177-226 aaHAMPHisKA: 234-290 aaHisKAHATPase_c: 334-439 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[177-226] | HisKA[234-290] | HATPase_c[334-439]
  • Domain count: 3
  • Matched identifier: HKOC_1957158
  • Positioned domains: HAMP 177-226 ; HisKA 234-290 ; HATPase_c 334-439
Cluster members and taxonomy
Visualization

Representative gene: GCF_030346725#QT350_RS08200

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 373 384 · GCF_000013585
AssemblyASM1358v1 · Complete Genomehaploid
Genome composition4 574 284 bp · 51,0% GCShigella flexneri 5 str. 8401
Signal transduction countsGenes 55 · HK 25 · RR 30CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusShigella
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Shigella

Related genes

Preview from the same derived genome key