Gene detail

SFV_RS13520

Histidine kinase, Unorthodox

Shigella flexneri 5 str. 8401 · GCF_000013585

ClassHKTypeUnorthodoxLength1197 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000013585#SFV_RS13520Stable P2CS identifier used across views.
GenomeGCF_000013585Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Shigella
Selected clusterHKOC_0161015Run 6 · 102 sequences · id 100% · cov 80% · representative
External referencesWP_005070035.1 · Q0T2C7 · MIST4 SFV_RS13520RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

PBPbHisKAHATPase_cResponse_regHpt
Protein length1197 aaLength used to scale native and Biotite-like views.
Annotated domains66 with usable coordinates.
Domain coverage797 / 1197 aa (66.6%)Merged over positioned domains only.
Domain description2 PBPb,1 HisKA,1 HATPase_c,1 Response_reg,1 HptSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa1197 aa
PBPb: 73-276 aa (204 aa)1PBPb: 303-519 aa (217 aa)2HisKA: 711-777 aa (67 aa)3HATPase_c: 825-938 aa (114 aa)4Response_reg: 961-1070 aa (110 aa)5Hpt: 1104-1188 aa (85 aa)6
Domain-by-domain annotation6 items
1 PBPb#1
73-276 aa · 204 aa · 17.0% of protein
Raw tokenPBPb:73:0.00000000000000194:276:209:219
2 PBPb#2
303-519 aa · 217 aa · 18.1% of protein
Raw tokenPBPb:303:8.1e-40:519:224:219
3 HisKA#3
711-777 aa · 67 aa · 5.6% of protein
Raw tokenHisKA:711:1.9e-16:777:67:64
4 HATPase_c#4
825-938 aa · 114 aa · 9.5% of protein
Raw tokenHATPase_c:825:1.03e-31:938:114:109
5 Response_reg#5
961-1070 aa · 110 aa · 9.2% of protein
Raw tokenResponse_reg:961:1.18e-39:1070:110:111
6 Hpt#6
1104-1188 aa · 85 aa · 7.1% of protein
Raw tokenHpt:1104:0.000000404:1188:85:84
  • Raw architecture: PBPb:73:0.00000000000000194:276:209:219#PBPb:303:8.1e-40:519:224:219#HisKA:711:1.9e-16:777:67:64#HATPase_c:825:1.03e-31:938:114:109#Response_reg:961:1.18e-39:1070:110:111#Hpt:1104:0.000000404:1188:85:84
  • Domain description: 2 PBPb,1 HisKA,1 HATPase_c,1 Response_reg,1 Hpt
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000013585::NC_008258.1::G00021
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2480558-2484770Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSFV_2429RefSeq proteinWP_005070035.1
Context group IDGCF_000013585::NC_008258.1::G00021
Context members
SFV_RS13515SFV_RS13520
Partner locus tags
SFV_RS13515SFV_RS13520
Partner old locus tags
SFV_2428SFV_2429
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_005070035.1Primary protein accession used for annex mappings.
UniProt accessionQ0T2C7Primary UniProt accession resolved in the annex database.
UniProt IDQ0T2C7_SHIF8Display identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagSFV_RS13520Primary locus identifier stored in the genes table.
Old locus tagSFV_2429Legacy locus tag recovered from the local context mapping.
Contig / repliconNC_008258.1Sequence record reported by the local genomic context database.
Genomic interval2 481 177-2 484 770 nt3 594 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span2 480 558-2 484 770 ntGCF_000013585::NC_008258.1::G00021

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000013585::NC_008258.1::G00021

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_008258.1All displayed genes belong to this local TCS context.
Neighborhood span2 480 558-2 484 770 nt4 213 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 480 558 nt2 484 770 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

SFV_RS13515GCF_000013585#SFV_RS13515
RRunclassified

2 480 558-2 481 172 nt · Forward (+)

Old locus SFV_2428RefSeq WP_000991377.1
SFV_RS13520GCF_000013585#SFV_RS13520
HKUnorthodoxCurrent focus

2 481 177-2 484 770 nt · Forward (+)

Old locus SFV_2429RefSeq WP_005070035.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0161015Run 6 · HK · 102 sequences
Representative sequenceGCF_000013585#SFV_RS13520The current gene is the representative for this cluster.
PFAM architectureSBP_bac_3 + SBP_bac_3 + HisKA + HATPase_c + Response_reg5 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0161015

Simplified PFAM architecture for HKOC_0161015

PFAM domain coverage: 720 / 1197 aa (60.2%)

1 aa1197 aa
SBP_bac_3: 62-276 aaSBP_bac_3SBP_bac_3: 306-520 aaSBP_bac_3HisKA: 711-777 aaHisKAHATPase_c: 825-937 aaHATPase_cResponse_reg: 961-1070 aaResponse_reg
SBP_bac_3SBP_bac_3HisKAHATPase_cResponse_reg
  • Simplified architecture: SBP_bac_3 + SBP_bac_3 + HisKA + HATPase_c + Response_reg
  • Raw architecture: SBP_bac_3[62-276] | SBP_bac_3[306-520] | HisKA[711-777] | HATPase_c[825-937] | Response_reg[961-1070]
  • Domain count: 5
  • Matched identifier: HKOC_0161015
  • Positioned domains: SBP_bac_3 62-276 ; SBP_bac_3 306-520 ; HisKA 711-777 ; HATPase_c 825-937 ; Response_reg 961-1070
Cluster members and taxonomy
Visualization

Representative gene: GCF_000013585#SFV_RS13520

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 373 384 · GCF_000013585
AssemblyASM1358v1 · Complete Genomehaploid
Genome composition4 574 284 bp · 51,0% GCShigella flexneri 5 str. 8401
Signal transduction countsGenes 55 · HK 25 · RR 30CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusShigella
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Shigella

Related genes

Preview from the same derived genome key