1 PAS#1
98-194 aa · 97 aa · 22.5% of protein
Raw token
PAS:98:0.00000000000245:194:113:113P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
ECO111_RS02215
Histidine kinase, Classic
Escherichia coli O111:H- str. 11128 · GCF_000010765
ClassHKTypeClassicLength431 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000010765#ECO111_RS02215Stable P2CS identifier used across views.
GenomeGCF_000010765Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Domain signature
Compact overview inferred from the domain field
PASHisKAHATPase_c
Protein length431 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage275 / 431 aa (63.8%)Merged over positioned domains only.
Domain description1 PAS,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa431 aa
Domain-by-domain annotation3 items
2 HisKA#2
203-268 aa · 66 aa · 15.3% of protein
Raw token
HisKA:203:6.35e-20:268:66:643 HATPase_c#3
313-424 aa · 112 aa · 26.0% of protein
Raw token
HATPase_c:313:4.14e-33:424:112:109- Raw architecture: PAS:98:0.00000000000245:194:113:113#HisKA:203:6.35e-20:268:66:64#HATPase_c:313:4.14e-33:424:112:109
- Domain description: 1 PAS,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000010765::NC_013364.1::G00001
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span456862-458904Genomic interval covered by the local TCS group.
Identifiers
Old locus tagECO111_0429RefSeq proteinWP_000893632.1
Context group ID
GCF_000010765::NC_013364.1::G00001Context members
ECO111_RS02210ECO111_RS02215
Partner locus tags
ECO111_RS02210ECO111_RS02215
Partner old locus tags
ECO111_0428ECO111_0429
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_000893632.1Primary protein accession used for annex mappings.
UniProt accessionA0AB33HTJ5Primary UniProt accession resolved in the annex database.
UniProt IDA0AB33HTJ5_ECOLXDisplay identifier provided by UniProt.
GO / PubMed7 / 0Unique GO terms and literature references available below.
Reference hubs
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagECO111_RS02215Primary locus identifier stored in the genes table.
Old locus tagECO111_0429Legacy locus tag recovered from the local context mapping.
Contig / repliconNC_013364.1Sequence record reported by the local genomic context database.
Genomic interval457 609-458 904 nt1 296 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span456 862-458 904 ntGCF_000010765::NC_013364.1::G00001
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000010765::NC_013364.1::G00001Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_013364.1All displayed genes belong to this local TCS context.
Neighborhood span456 862-458 904 nt2 043 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
456 862 nt458 904 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
ECO111_RS02210GCF_000010765#ECO111_RS02210
RROmpR
456 862-457 551 nt · Forward (+)
ECO111_RS02215GCF_000010765#ECO111_RS02215
HKClassicCurrent focus
457 609-458 904 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000010765#ECO111_RS02215The current gene is the representative for this cluster.
PFAM architecturePhoR + PAS + HisKA + HATPase_c4 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2161304
Simplified PFAM architecture for HKOC_2161304
PFAM domain coverage: 360 / 431 aa (83.5%)
1 aa431 aa
PhoRPASHisKAHATPase_c
- Simplified architecture: PhoR + PAS + HisKA + HATPase_c
- Raw architecture: PhoR[6-91] | PAS[99-194] | HisKA[203-268] | HATPase_c[313-424]
- Domain count: 4
- Matched identifier: HKOC_2161304
- Positioned domains: PhoR 6-91 ; PAS 99-194 ; HisKA 203-268 ; HATPase_c 313-424
Cluster members and taxonomy
Representative gene: GCF_000010765#ECO111_RS02215
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 585 396 · GCF_000010765
AssemblyASM1076v1 · Complete Genomehaploid
Genome composition5 766 081 bp · 50,5% GCEscherichia coli O111:H- str. 11128
Signal transduction countsGenes 59 · HK 29 · RR 30CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia
Related genes
Preview from the same derived genome key