Gene detail

BA_RS10650

Histidine kinase, Classic

Bacillus anthracis str. Ames · GCF_000007845

ClassHKTypeClassicLength452 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000007845#BA_RS10650Stable P2CS identifier used across views.
GenomeGCF_000007845Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus
Selected clusterHKOC_1936932Run 6 · 355 sequences · id 100% · cov 80% · representative
External referencesWP_000694896.1 · A0A6H3AHX4 · MIST4 BA_RS10650RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length452 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage242 / 452 aa (53.5%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa452 aa
HAMP: 158-229 aa (72 aa)1HisKA: 233-295 aa (63 aa)2HATPase_c: 343-449 aa (107 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
158-229 aa · 72 aa · 15.9% of protein
Raw tokenHAMP:158:0.00000000123:229:72:69
2 HisKA#2
233-295 aa · 63 aa · 13.9% of protein
Raw tokenHisKA:233:0.0000000000000118:295:63:64
3 HATPase_c#3
343-449 aa · 107 aa · 23.7% of protein
Raw tokenHATPase_c:343:4.96e-31:449:108:109
  • Raw architecture: HAMP:158:0.00000000123:229:72:69#HisKA:233:0.0000000000000118:295:63:64#HATPase_c:343:4.96e-31:449:108:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000007845::NC_003997.3::G00023
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2065368-2067413Genomic interval covered by the local TCS group.
Identifiers
Old locus tagBA2213%2CBA_2213RefSeq proteinWP_000694896.1
Context group IDGCF_000007845::NC_003997.3::G00023
Context members
BA_RS10645BA_RS10650
Partner locus tags
BA_RS10645BA_RS10650
Partner old locus tags
BA2212%2CBA_2212BA2213%2CBA_2213
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_000694896.1Primary protein accession used for annex mappings.
UniProt accessionA0A6H3AHX4Primary UniProt accession resolved in the annex database.
UniProt IDA0A6H3AHX4_BACANDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagBA_RS10650Primary locus identifier stored in the genes table.
Old locus tagBA2213%2CBA_2213Legacy locus tag recovered from the local context mapping.
Contig / repliconNC_003997.3Sequence record reported by the local genomic context database.
Genomic interval2 066 055-2 067 413 nt1 359 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span2 065 368-2 067 413 ntGCF_000007845::NC_003997.3::G00023

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000007845::NC_003997.3::G00023

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_003997.3All displayed genes belong to this local TCS context.
Neighborhood span2 065 368-2 067 413 nt2 046 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 065 368 nt2 067 413 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

BA_RS10645GCF_000007845#BA_RS10645
RROmpR

2 065 368-2 066 051 nt · Forward (+)

Old locus BA2212%2CBA_2212RefSeq WP_000504574.1
BA_RS10650GCF_000007845#BA_RS10650
HKClassicCurrent focus

2 066 055-2 067 413 nt · Forward (+)

Old locus BA2213%2CBA_2213RefSeq WP_000694896.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1936932Run 6 · HK · 355 sequences
Representative sequenceGCF_000007845#BA_RS10650The current gene is the representative for this cluster.
PFAM architectureArlS_N + HAMP + HisKA + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1936932

Simplified PFAM architecture for HKOC_1936932

PFAM domain coverage: 324 / 452 aa (71.7%)

1 aa452 aa
ArlS_N: 51-151 aaArlS_NHAMP: 176-228 aaHAMPHisKA: 234-296 aaHisKAHATPase_c: 343-449 aaHATPase_c
ArlS_NHAMPHisKAHATPase_c
  • Simplified architecture: ArlS_N + HAMP + HisKA + HATPase_c
  • Raw architecture: ArlS_N[51-151] | HAMP[176-228] | HisKA[234-296] | HATPase_c[343-449]
  • Domain count: 4
  • Matched identifier: HKOC_1936932
  • Positioned domains: ArlS_N 51-151 ; HAMP 176-228 ; HisKA 234-296 ; HATPase_c 343-449
Cluster members and taxonomy
Visualization

Representative gene: GCF_000007845#BA_RS10650

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 198 094 · GCF_000007845
AssemblyASM784v1 · Complete Genomehaploid
Genome composition5 227 293 bp · 35,5% GCBacillus anthracis str. Ames
Signal transduction countsGenes 94 · HK 46 · RR 47CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderBacillalesFamilyBacillaceaeGenusBacillus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Bacillales6Bacillaceae7Bacillus

Related genes

Preview from the same derived genome key