1 Response_reg#1
9-121 aa · 113 aa · 52.6% of protein
Raw token
Response_reg:9:2.84e-36:121:113:111P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
C_RS12960
Response regulator, unclassified
Escherichia coli CFT073 · GCF_000007445
ClassRRTypeunclassifiedLength215 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000007445#C_RS12960Stable P2CS identifier used across views.
GenomeGCF_000007445Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Domain signature
Compact overview inferred from the domain field
Response_regGerE
Protein length215 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage170 / 215 aa (79.1%)Merged over positioned domains only.
Domain description1 Response_reg,1 GerESummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa215 aa
Domain-by-domain annotation2 items
2 GerE#2
152-208 aa · 57 aa · 26.5% of protein
Raw token
GerE:152:3.1e-25:208:57:57- Raw architecture: Response_reg:9:2.84e-36:121:113:111#GerE:152:3.1e-25:208:57:57
- Domain description: 1 Response_reg,1 GerE
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelorphanGCF_000007445::NC_004431.1::G00016
Group size11 locus tag listed below.
HK / RR0 / 1Counts resolved for the local TCS neighborhood.
Context span2578184-2578831Genomic interval covered by the local TCS group.
Identifiers
Old locus tagc2730RefSeq proteinWP_001113641.1
Context group ID
GCF_000007445::NC_004431.1::G00016Context members
C_RS12960
Partner locus tags
C_RS12960
Partner old locus tags
c2730
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_001113641.1Primary protein accession used for annex mappings.
UniProt accessionB7MXM3Primary UniProt accession resolved in the annex database.
UniProt IDB7MXM3_ECO81Display identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
Reference hubs
GO terms
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagC_RS12960Primary locus identifier stored in the genes table.
Old locus tagc2730Legacy locus tag recovered from the local context mapping.
Contig / repliconNC_004431.1Sequence record reported by the local genomic context database.
Genomic interval2 578 184-2 578 831 nt648 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span2 578 184-2 578 831 ntGCF_000007445::NC_004431.1::G00016
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000007445::NC_004431.1::G00016Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_004431.1All displayed genes belong to this local TCS context.
Neighborhood span2 578 184-2 578 831 nt648 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 578 184 nt2 578 831 nt
Neighborhood gene cards
1 gene in the current local neighborhood.
C_RS12960GCF_000007445#C_RS12960
RRunclassifiedCurrent focus
2 578 184-2 578 831 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000007445#C_RS12960The current gene is the representative for this cluster.
PFAM architectureResponse_reg + GerE2 domains in the representative PFAM annotation.
PFAM architecture for RROC_1906489
Simplified PFAM architecture for RROC_1906489
PFAM domain coverage: 169 / 215 aa (78.6%)
1 aa215 aa
Response_regGerE
- Simplified architecture: Response_reg + GerE
- Raw architecture: Response_reg[9-121] | GerE[152-207]
- Domain count: 2
- Matched identifier: RROC_1906489
- Positioned domains: Response_reg 9-121 ; Response_reg 9-121 ; GerE 152-207 ; GerE 152-207
Cluster members and taxonomy
Representative gene: GCF_000007445#C_RS12960
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 199 310 · GCF_000007445
AssemblyASM744v1 · Complete Genomehaploid
Genome composition5 231 428 bp · 50,5% GCEscherichia coli CFT073
Signal transduction countsGenes 68 · HK 33 · RR 35CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia
Related genes
Preview from the same derived genome key