1 GAF#1
236-360 aa · 125 aa · 21.5% of protein
Raw token
GAF:236:0.00000308:360:134:133P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
SAG_RS03640
Histidine kinase, Classic
Streptococcus agalactiae 2603V/R · GCF_000007265
ClassHKTypeClassicLength581 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000007265#SAG_RS03640Stable P2CS identifier used across views.
GenomeGCF_000007265Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus
Domain signature
Compact overview inferred from the domain field
GAFHis_kinaseHATPase_c
Protein length581 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage305 / 581 aa (52.5%)Merged over positioned domains only.
Domain description1 GAF,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa581 aa
Domain-by-domain annotation3 items
2 His_kinase#2
371-449 aa · 79 aa · 13.6% of protein
Raw token
His_kinase:371:6.03e-30:449:80:803 HATPase_c#3
468-568 aa · 101 aa · 17.4% of protein
Raw token
HATPase_c:468:0.00000000000283:568:105:109- Raw architecture: GAF:236:0.00000308:360:134:133#His_kinase:371:6.03e-30:449:80:80#HATPase_c:468:0.00000000000283:568:105:109
- Domain description: 1 GAF,1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000007265::NC_004116.1::G00002
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span199906-202372Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSAG0182RefSeq proteinWP_000930334.1
Context group ID
GCF_000007265::NC_004116.1::G00002Context members
SAG_RS03640SAG_RS03645
Partner locus tags
SAG_RS03640SAG_RS03645
Partner old locus tags
SAG0182SAG0183
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_000930334.1Primary protein accession used for annex mappings.
UniProt accessionA0AAV3JGV1Primary UniProt accession resolved in the annex database.
UniProt IDA0AAV3JGV1_STRAGDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.
Reference hubs
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagSAG_RS03640Primary locus identifier stored in the genes table.
Old locus tagSAG0182Legacy locus tag recovered from the local context mapping.
Contig / repliconNC_004116.1Sequence record reported by the local genomic context database.
Genomic interval199 906-201 651 nt1 746 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span199 906-202 372 ntGCF_000007265::NC_004116.1::G00002
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000007265::NC_004116.1::G00002Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_004116.1All displayed genes belong to this local TCS context.
Neighborhood span199 906-202 372 nt2 467 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
199 906 nt202 372 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
SAG_RS03640GCF_000007265#SAG_RS03640
HKClassicCurrent focus
199 906-201 651 nt · Forward (+)
SAG_RS03645GCF_000007265#SAG_RS03645
RRLytTR
201 632-202 372 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000007265#SAG_RS03640The current gene is the representative for this cluster.
PFAM architecture5TM-5TMR_LYT + His_kinase + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1156582
Simplified PFAM architecture for HKOC_1156582
PFAM domain coverage: 356 / 581 aa (61.3%)
1 aa581 aa
5TM-5TMR_LYTHis_kinaseHATPase_c
- Simplified architecture: 5TM-5TMR_LYT + His_kinase + HATPase_c
- Raw architecture: 5TM-5TMR_LYT[25-200] | His_kinase[371-449] | HATPase_c[469-569]
- Domain count: 3
- Matched identifier: HKOC_1156582
- Positioned domains: 5TM-5TMR_LYT 25-200 ; His_kinase 371-449 ; HATPase_c 469-569
Cluster members and taxonomy
Representative gene: GCF_000007265#SAG_RS03640
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 208 435 · GCF_000007265
AssemblyASM726v1 · Complete Genomehaploid
Genome composition2 160 267 bp · 35,5% GCStreptococcus agalactiae 2603V/R
Signal transduction countsGenes 38 · HK 18 · RR 20CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyStreptococcaceaeGenusStreptococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Streptococcaceae7Streptococcus
Related genes
Preview from the same derived genome key